24-2109
3-Methyl-1-phenyl-2-pyrazoline-5-one
Synonym(s):
5-Methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one
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About This Item
Empirical Formula (Hill Notation):
C10H10N2O
CAS Number:
Molecular Weight:
174.20
EC Number:
201-891-0
UNSPSC Code:
12352005
PubChem Substance ID:
Beilstein/REAXYS Number:
609575
MDL number:
Bp:
287 °C/265 mmHg (lit.)
InChI key
QELUYTUMUWHWMC-UHFFFAOYSA-N
InChI
1S/C10H10N2O/c1-8-7-10(13)12(11-8)9-5-3-2-4-6-9/h2-6H,7H2,1H3
SMILES string
CC1=NN(C(=O)C1)c2ccccc2
form
solid
availability
available only in Japan
dilution
(for analytical testing)
bp
287 °C/265 mmHg (lit.)
application(s)
peptide synthesis
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Application
environmental analysis
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 1
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Manabu Ohta et al.
Brain research, 1490, 184-192 (2012-09-18)
Traumatic axonal injury (TAI), a feature of traumatic brain injury (TBI), progressively evolves over hours through impaired axonal transport and is thought to be a major contributor to cognitive dysfunction. In spite of various studies suggesting that pharmacologic or physiologic
Laura Monturiol-Gross et al.
The Journal of infectious diseases, 206(8), 1218-1226 (2012-08-21)
Clostridium perfringens, the most broadly distributed pathogen in nature, produces a prototype phospholipase C, also called α-toxin, which plays a key role in the pathogenesis of gas gangrene. α-Toxin causes plasma membrane disruption at high concentrations, but the role of
Ajmal Ahmad et al.
Molecular and cellular biochemistry, 367(1-2), 215-225 (2012-06-01)
Stroke is a life-threatening disease with major cause of mortality and morbidity worldwide. The neuronal damage following cerebral ischemia is a serious risk to stroke patients. Oxidative stress and apoptotic damage play an important role in cerebral ischemic pathogenesis and
Mitsugi Shimoda et al.
World journal of gastroenterology, 18(27), 3520-3526 (2012-07-25)
To investigate the effect of E3-methyl-1-phenyl-2-pyrazolin-5-one (Edr) on hepatic ischemia-reperfusion (I/R) injury and liver regeneration in a porcine hepatectomy model. One hour ischemia was induced by occluding the vessels and the bile duct of the right and median lobes. A
Guibin Wang et al.
Neuroscience letters, 543, 72-77 (2013-04-09)
Edaravone, a free radical scavenger, is the first clinical drug of neuroprotection for ischemic stroke patients in the world, and has been shown to be an effective agent to alleviate cerebral ischemic injury. It has been established that acidosis is
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