30-0180
Taurine
SAJ first grade, ≥98.5%
Synonym(s):
2-Aminoethanesulfonic acid
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About This Item
Linear Formula:
NH2CH2CH2SO3H
CAS Number:
Molecular Weight:
125.15
PubChem Substance ID:
UNSPSC Code:
12352116
Beilstein/REAXYS Number:
1751215
MDL number:
Assay:
≥98.5%
Grade:
SAJ first grade
Form:
solid
SMILES string
NCCS(O)(=O)=O
InChI key
XOAAWQZATWQOTB-UHFFFAOYSA-N
InChI
1S/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6)
grade
SAJ first grade
assay
≥98.5%
form
solid
availability
available only in Japan
pH
4.5-6.0 (25 °C, 62.6 g/L)
mp
>300 °C (lit.)
storage temp.
15-25°C
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Biochem/physiol Actions
Non-selective endogenous agonist at glycine receptors.
Non-selective endogenous agonist at glycine receptors. Conditionally essential sulfonated amino acid which modulates apoptosis in some cells; functions in many metabolic activities; a product of methionine and cysteine metabolism.
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Marlene Wewalka et al.
The Journal of clinical endocrinology and metabolism, 99(4), 1442-1451 (2014-01-18)
Bile acids (BAs) are newly recognized signaling molecules in glucose and energy homeostasis. Differences in BA profiles with type 2 diabetes mellitus (T2D) remain incompletely understood. The objective of the study was to assess serum BA composition in impaired glucose-tolerant
Felizia K Voss et al.
Science (New York, N.Y.), 344(6184), 634-638 (2014-05-03)
Regulation of cell volume is critical for many cellular and organismal functions, yet the molecular identity of a key player, the volume-regulated anion channel VRAC, has remained unknown. A genome-wide small interfering RNA screen in mammalian cells identified LRRC8A as
Mette Møller Handrup et al.
Pediatric blood & cancer, 60(8), 1292-1298 (2013-02-19)
To determine if the catheter lock taurolidine can reduce the number of catheter-related bloodstream infections (CRBSI) in pediatric cancer patients with tunneled central venous catheters (CVC). During a study period of 34 months, 129 newly placed tunneled CVCs in 112
Jacob Bak Holm et al.
American journal of physiology. Cell physiology, 305(1), C48-C60 (2013-03-15)
Pathophysiological conditions challenge cell volume homeostasis and perturb cell volume regulatory mechanisms leading to alterations of cell metabolism, active transepithelial transport, cell migration, and death. We report that inhibition of the 5-lipoxygenase (5-LO) with AA861 or ETH 615-139, the cysteinyl
M Axelson et al.
Hepatology (Baltimore, Md.), 31(6), 1305-1312 (2000-05-29)
The biosynthesis of bile acids by primary cultures of normal human hepatocytes has been investigated. A general and sensitive method for the isolation and analysis of sterols and bile acids was used, based on anion exchange chromatography and gas chromatography-mass
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