00176
Sulfadimethoxine solution
1 mg/mL in H2O
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About This Item
Empirical Formula (Hill Notation):
C12H14N4O4S
CAS Number:
Molecular Weight:
310.33
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Beilstein/REAXYS Number:
306856
concentration
1 mg/mL in H2O
mode of action
DNA synthesis | interferes, enzyme | inhibits
SMILES string
COc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(OC)n1
General description
Chemical structure: sulfonamide
Regulatory Information
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New ferrocenic pyrrolo[1,2-a]quinoxaline derivatives: synthesis, and in vitro antimalarial activity.
Jean Guillon et al.
Bioorganic & medicinal chemistry, 16(20), 9133-9144 (2008-09-30)
Following our search for antimalarial compounds, novel series of ferrocenic pyrrolo[1,2-a]quinoxaline derivatives 1-2 were synthesized from various substituted nitroanilines and tested for in vitro activity upon the erythrocytic development of Plasmodiumfalciparum strains with different chloroquine-resistance status. The pyrrolo[1,2-a]quinoxalines 1 were
Jody L Floyd et al.
Antimicrobial agents and chemotherapy, 54(12), 5406-5412 (2010-09-22)
A multidrug efflux pump designated LmrS (lincomycin resistance protein of Staphylococcus aureus), belonging to the major facilitator superfamily (MFS) of transporters, was cloned, and the role of LmrS in antimicrobial efflux was evaluated. The highest relative increase in MIC, 16-fold
Giorgio Ottaviani et al.
Journal of medicinal chemistry, 50(4), 742-748 (2007-02-16)
The development of in silico and in vitro tools to estimate or predict the passive human skin permeation and distribution of new chemical entities, useful in dermal drug delivery, in absorption studies of toxic compounds, and in the cosmetics industry
Naomi L Kruhlak et al.
Toxicology mechanisms and methods, 18(2-3), 217-227 (2008-01-01)
ABSTRACT Drug-induced phospholipidosis (PL) is a condition characterized by the accumulation of phospholipids and drug in lysosomes, and is found in a variety of tissue types. PL is frequently manifested in preclinical studies and may delay or prevent the development
Alfonso Pérez-Garrido et al.
Bioorganic & medicinal chemistry, 17(2), 896-904 (2008-12-06)
This paper reports a QSAR study for predicting the complexation of a large and heterogeneous variety of substances (233 organic compounds) with beta-cyclodextrins (beta-CDs). Several different theoretical molecular descriptors, calculated solely from the molecular structure of the compounds under investigation
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 187062-5G | 04061838758392 |
| 187062-25G | 04061838758385 |
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