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00180

Acetamidine hydrochloride

Name: Acetamidine hydrochloride
Brand: SIAL

purum, ≥97.0% (NT)

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About This Item

Linear Formula:

CH₃C(=NH)NH₂ · HCl

CAS Number:

124-42-5

Molecular Weight:

94.54

EC Number:

204-700-9

UNSPSC Code:

12352100

MDL number:

MFCD00013016

Beilstein/REAXYS Number:

3591762

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grade

purum

assay

≥97.0% (NT)

mp

165-170 °C (lit.), 168-175 °C

SMILES string

Cl[H].CC(N)=N

InChI

1S/C2H6N2.ClH/c1-2(3)4;/h1H3,(H3,3,4);1H

InChI key

WCQOBLXWLRDEQA-UHFFFAOYSA-N

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Haloacetamidine-based inactivators of protein arginine deiminase 4 (PAD4): evidence that general acid catalysis promotes efficient inactivation.

Bryan Knuckley et al.

Chembiochem : a European journal of chemical biology, 11(2), 161-165 (2009-12-17)

Dysregulated protein arginine deiminase (PAD) activity, particularly PAD4, has been suggested to play a role in the onset and progression of numerous human diseases, including rheumatoid arthritis (RA). Given the potential role of PAD4 in RA, we set out to

Selective inhibition of iNOS by benzyl- and dibenzyl derivatives of N-(3-aminobenzyl)acetamidine.

Marialuigia Fantacuzzi et al.

ChemMedChem, 6(7), 1203-1206 (2011-05-14)

Catalytic properties of human urinary kallikrein.

E Antonini et al.

Biochemistry, 21(10), 2477-2482 (1982-05-11)

Kinetic studies have been carried out with a well-characterized preparation of human urinary (h.u.) kallikrein using chromogenic substrates. Steady-state and pre-steady-state data for h.u. kallikrein catalyzed hydrolysis of N alpha-carbobenzoxy-L-lysine p-nitrophenyl ester (ZLysONp) and of N alpha-carbobenzoxy-L-alanine p-nitrophenyl ester (ZAlaONp)

Differential effects of selective and non-selective inhibition of nitric oxide synthase on the expression and activity of cyclooxygenase-2 during gastric ulcer healing.

Jin Sheng Guo et al.

European journal of pharmacology, 536(3), 301-308 (2006-04-08)

Nitric oxide synthases (NOS) and cyclooxygenase-2 (COX-2) are important enzymes involved in ulcer healing but interactions between them have not been clearly defined. The aim of this study was to investigate the effects of selective or non-selective inhibition of NOS

Characterization and inactivation of an agmatine deiminase from Helicobacter pylori.

Justin E Jones et al.

Bioorganic chemistry, 38(2), 62-73 (2009-12-29)

Helicobacter pylori encodes a potential virulence factor, agmatine deiminase (HpAgD), which catalyzes the conversion of agmatine to N-carbamoyl putrescine (NCP) and ammonia - agmatine is decarboxylated arginine. Agmatine is an endogenous human cell signaling molecule that triggers the innate immune

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Global Trade Item Number

SKU	GTIN
270768-5G	04061826142899
270768-25G	04061826142868

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