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00617

2,6-Dichloroindophenol sodium salt hydrate

Name: 2,6-Dichloroindophenol sodium salt hydrate
Brand: SIAL

purum, ≥95.0% (calc. based on dry substance, NT)

Synonym(s):

2,6-Dichloro-N-(4-hydroxyphenyl)-1,4-benzoquinoneimine sodium salt, 2,6-Dichlorobenzenone-indophenol sodium salt, 2,6-Dichlorophenolindophenol sodium salt hydrate, DCIP, DPIP

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About This Item

Empirical Formula (Hill Notation):

C₁₂H₆Cl₂NNaO₂ · xH₂O

CAS Number:

1266615-56-8

Molecular Weight:

290.08 (anhydrous basis)

EC Number:

210-640-4

UNSPSC Code:

12352100

MDL number:

MFCD00150014

Beilstein/REAXYS Number:

3641229

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grade

purum

assay

≥95.0% (calc. based on dry substance, NT)

loss

≤14% loss on drying

application(s)

food and beverages

SMILES string

O.[Na+].[O-]c1ccc(cc1)\N=C2/C=C(Cl)C(=O)C(Cl)=C2

InChI

1S/C12H7Cl2NO2.Na.H2O/c13-10-5-8(6-11(14)12(10)17)15-7-1-3-9(16)4-2-7;;/h1-6,16H;;1H2/q;+1;/p-1

InChI key

XHSOLXWCGCVQHE-UHFFFAOYSA-M

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General description

2,6-Dichloroindophenol sodium salt hydrate is a blue redox dye. It is useful for vitamin C determination.

Application

2,6-Dichloroindophenol (DCIP) may be used in the following studies:

As redox dye to investigate the efficiency of gold nanoparticles (Au-NP) as redox mediator for glucose oxidase (GOx).
To compose UVB specific dosimeter.
Quantification of vitamin C (L-ascorbic acid) in fruit juices.
As substrate in NQO1 assay to investigate the liver cytosolic NQO1 activity spectrophotometrically.
Mitochondrial succinate CoQ oxidoreductase (complex II) activity assay.

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Dopamine modulates mitochondrial function in viable SH-SY5Y cells possibly via its interaction with complex I: relevance to dopamine pathology in schizophrenia.

Hanit Brenner-Lavie et al.

Biochimica et biophysica acta, 1777(2), 173-185 (2007-11-13)

Deleterious effects of dopamine (DA) involving mitochondrial dysfunction have an important role in DA-associated neuronal disorders, including schizophrenia and Parkinson's disease. DA detrimental effects have been attributed to its ability to be auto-oxidized to toxic reactive oxygen species. Since, unlike

Comparison of citrus coumarins on carcinogen-detoxifying enzymes in Nrf2 knockout mice.

Misty Prince et al.

Toxicology letters, 185(3), 180-186 (2009-01-20)

Naturally occurring coumarins possess anti-carcinogenic activities in part by inducing carcinogen-detoxifying enzymes glutathione S-transferase (GST) and/or NAD(P)H quinone oxidoreductase (NQO1). Our goal was to determine whether citrus coumarins induce hepatic GST and/or NQO1 via activation of Nrf2 and the antioxidant

Spectrophotometric evaluation of gold nanoparticles as red-ox mediator for glucose oxidase.

Ramanaviciene A, et al.

Sensors and Actuators B, Chemical, 137(2), 483-489 (2009)

Further insights toward vitamin c determination and stability proposal of a new quantification method

Vieira CA, et al.

Biosci., 26(2), 296-304 (2010)

UV dosimeter based on dichloroindophenol and tin(IV) oxide.

Andrew Mills et al.

The Analyst, 134(5), 845-850 (2009-04-22)

A UVB specific dosimeter is described comprising: a redox dye (2,6-dichloroindophenol, DCIP), a semiconductor (tin(IV) oxide, SnO(2)) and a sacrificial electron donor (glycerol) dispersed in a polymer (hydroxy ethyl cellulose, HEC) film. The dosimeter is blue in the absence of

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Global Trade Item Number

SKU	GTIN
305111-5G	04061832287140

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