00652
Iodoacetic acid
puriss. p.a., ≥99.5% (T)
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About This Item
Linear Formula:
ICH2CO2H
CAS Number:
Molecular Weight:
185.95
EC Number:
200-590-1
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
1739079
MDL number:
grade
puriss. p.a.
assay
≥99.5% (T)
impurities
≤0.1% water
ign. residue
≤0.02% (as SO4)
mp
77-79 °C (lit.), 80-84 °C
anion traces
iodide (I-): ≤0.01%
cation traces
Cd: ≤1 mg/kg, Cu: ≤1 mg/kg, Fe: ≤1 mg/kg, Pb: ≤1 mg/kg, Zn: ≤1 mg/kg
storage temp.
2-8°C
SMILES string
OC(=O)CI
InChI
1S/C2H3IO2/c3-1-2(4)5/h1H2,(H,4,5)
InChI key
JDNTWHVOXJZDSN-UHFFFAOYSA-N
Application
Reagent for the modification of cysteine residues in proteins.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Eye Dam. 1 - Skin Corr. 1A
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Regulatory Information
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Devi Rani Sagar et al.
Annals of the rheumatic diseases, 73(8), 1558-1565 (2013-06-01)
Increased subchondral bone turnover may contribute to pain in osteoarthritis (OA). To investigate the analgesic potential of a modified version of osteoprotegerin (osteoprotegerin-Fc (OPG-Fc)) in the monosodium iodoacetate (MIA) model of OA pain. Male Sprague Dawley rats (140-260 g) were treated
X D Wang et al.
Journal of dental research, 92(10), 918-924 (2013-08-13)
Temporomandibular joint osteoarthritis (TMJOA) is clinically characterized by female preponderance, with a female-to-male ratio of more than 2:1; however, the underlying mechanism remains obscure. We examined the effects of estrogen on TMJOA induced by monosodium iodoacetate. Female rats were randomly
Catherine E Ferland et al.
Phytotherapy research : PTR, 26(9), 1278-1285 (2012-09-28)
The aim of the present study was to evaluate whether eugenol, the main constituent of clove oil, has the capacity to provide analgesia in the monoiodoacetate-induced rat model of osteoarthritis. Animals (n = 6/group) received either eugenol (20 or 40 mg/kg) or a