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Merck
CN

00681

Phthaldialdehyde

puriss. p.a., ≥98.5% (HPLC)

Synonym(s):

o-Phthalaldehyde, o-Phthalic dicarboxaldehyde, Benzene-1,2-dicarboxaldehyde, OPA

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About This Item

Empirical Formula (Hill Notation):
C8H6O2
CAS Number:
643-79-8
Molecular Weight:
134.13
EC Number:
211-402-2
UNSPSC Code:
12352100
PubChem Substance ID:
24844938
Beilstein/REAXYS Number:
878317
MDL number:
MFCD00003335

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InChI key

ZWLUXSQADUDCSB-UHFFFAOYSA-N

InChI

1S/C8H6O2/c9-5-7-3-1-2-4-8(7)6-10/h1-6H

SMILES string

O=Cc1ccccc1C=O

grade

puriss. p.a.

assay

≥98.5% (HPLC)

impurities

≤0.5% phthalic acid

ign. residue

≤0.1% (as SO4)

mp

54-56 °C

cation traces

Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg

storage temp.

2-8°C

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Biochem/physiol Actions

Phthaldialdehyde can be used for the pre-column derivatization of amino acids for high-performance liquid chromatography (HPLC) separation. It may also be used for flow cytometric measurements of protein thiol groups.

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Danger

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

269.6 °F - closed cup

flash_point_c

132 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

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Jong-Suk Song et al.
Investigative ophthalmology & visual science, 53(10), 6164-6170 (2012-08-18)
We evaluated whether viscoelastics have protective effects on the corneal endothelial cell damage in a toxic anterior segment syndrome (TASS) animal model depending on the types of viscoelastics. A TASS animal model was established with an injection of 0.1 mL
Gianni Pala et al.
Expert review of clinical immunology, 9(3), 227-234 (2013-03-01)
This study summarizes and reviews the available health information on ortho-phthalaldehyde (OPA), a recently introduced and widespread disinfectant for heat-sensitive medical equipment, particularly focusing on its possible immunological effects in the healthcare setting. OPA properties derived from laboratory and clinical
A Pappa-Louisi et al.
Talanta, 85(4), 2241-2245 (2011-08-30)
In an effort to enhance complex mixture separations by using small amounts of a homologous series of alkanols as additives in the mobile phases, it was proposed an optimization algorithm based on a sixth-parameter retention model. This model considers simultaneously
Michal Douša et al.
Journal of pharmaceutical and biomedical analysis, 66, 359-364 (2012-04-06)
A rapid procedure based on direct extraction and HILIC separation of aliskiren (ALI) degradation product - 3-amino-2,2-dimethylpropanamide (ADPA) with fluorescence detection has been developed. The formation of ADPA from ALI under different conditions was studied. The evaluation of HILIC method
M M Ayyash et al.
Journal of food science, 77(8), M490-M498 (2012-07-20)
The effect of NaCl substitution with KCl at different pH levels (6.0, 5.5, and 5.0) and salt concentrations on proteinase activities of cell-free and supernatant of Lactobacillus delbrueckii ssp. bulgaricus 11824 (L. bulgaricus) and Streptococcus thermophilus MS (ST) was investigated.
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