01190
N-Acetyl-DL-homocysteine thiolactone
≥99.0% (N)
Synonym(s):
2-Acetamido-4-mercaptobutyric acid γ-thiolactone
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About This Item
Empirical Formula (Hill Notation):
C6H9NO2S
CAS Number:
Molecular Weight:
159.21
UNSPSC Code:
12352100
EC Number:
214-793-8
Beilstein/REAXYS Number:
4338
MDL number:
assay
≥99.0% (N)
ign. residue
≤0.05%
mp
109-111 °C
SMILES string
CC(=O)NC1CCSC1=O
Other Notes
Reagent for the thiolation of proteins
signalword
Danger
hcodes
pcodes
Hazard Classifications
Acute Tox. 3 Oral
Storage Class
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Regulatory Information
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S M Naqvi et al.
Neuroreport, 2(1), 61-63 (1991-01-01)
The present study was undertaken to evaluate the neurotoxic effects of the organophosphate, phosphamidon, on glutathione-S-transferase (GST) activity and concentration of sulphhydryl groups, and to study the possible protection against these effects by the simultaneous administration of the antioxidant, acetylhomocysteine
N Emonet et al.
Journal of photochemistry and photobiology. B, Biology, 40(1), 84-90 (1997-08-01)
The sensitivity of human dermal fibroblasts to UVA radiation has been linked to a decrease in intracellular glutathione (GSH) levels. GSH (gamma-glutamyl-cysteinyl-glycine) is a radical scavenger and a cofactor for protective enzymes such as selenium-dependent GSH peroxidases. In this study
Comparison of monothiols and vitamin therapy administered alone or in combinations during methylmercury poisoning.
C Bapu et al.
Bulletin of environmental contamination and toxicology, 52(2), 182-189 (1994-02-01)
G Papaccio et al.
Journal of cellular biochemistry, 71(4), 479-490 (1998-11-25)
This study showed that citiolone (CIT), a free radical scavenger, significantly increased superoxide dismutase (P < 0.001 vs. untreated NOD, NMMA-treated, and silica-treated animals), catalase (P < 0.01 vs. untreated NOD), and glutathione peroxidase (P < 0.001 vs. untreated NOD
[48] thiolation.
F H White
Methods in enzymology, 25, 541-546 (1972-01-01)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| D56209-100G | 04061833586518 |
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