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About This Item
Empirical Formula (Hill Notation):
C15H16O3
CAS Number:
Molecular Weight:
244.29
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
85151701
MDL number:
InChI
1S/C15H16O3/c1-10(2)4-7-12-13(17-3)8-5-11-6-9-14(16)18-15(11)12/h4-6,8-9H,7H2,1-3H3
SMILES string
COc1ccc2C=CC(=O)Oc2c1C\C=C(\C)C
InChI key
MBRLOUHOWLUMFF-UHFFFAOYSA-N
grade
primary reference standard
shelf life
limited shelf life, expiry date on the label
manufacturer/tradename
HWI
application(s)
food and beverages
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General description
Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.
Exact content by quantitative NMR can be found on the certificate.
Application
Reference Standard in the analysis of herbal medicinal products
Biochem/physiol Actions
Active constituent of Cnidium monnieri, a traditional Chinese medicine used for its anti-inflammatory, analgesic, and anti-lipedemic activities. Dramatically decreased lipid accumulation in a quail model. Its neuroprotective effect on MPP(+)-induced cytotoxicity in PC12 cells supports the use of osthole as a therapeutic agent for the treatment of neurodegenerative disorders. Suppression of fatty acid synthase expression in HER2-overexpressing breast cancer cells indicates osthole as a promising agent for chemotherapy.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Ola D Alabi et al.
Life sciences, 102(2), 105-110 (2014-03-25)
Osthole, a coumarin derivative, has been used in Chinese medicine and studies have suggested a potential use in treatment of diabetes and cancers. Therefore, we investigated the effects of osthole and other coumarins on GLUT1 activity in two cell lines
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