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Merck
CN

02228

4-Chloro-1,8-naphthalic anhydride

≥95.0% (T)

Synonym(s):

6-Chloronaphtho[1,8,8a-c,d]pyran-1,3-dione

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About This Item

Empirical Formula (Hill Notation):
C12H5ClO3
CAS Number:
Molecular Weight:
232.62
UNSPSC Code:
12352100
PubChem Substance ID:
EC Number:
223-760-7
MDL number:
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InChI key

UJEUBSWHCGDJQU-UHFFFAOYSA-N

InChI

1S/C12H5ClO3/c13-9-5-4-8-10-6(9)2-1-3-7(10)11(14)16-12(8)15/h1-5H

SMILES string

Clc1ccc2C(=O)OC(=O)c3cccc1c23

assay

≥95.0% (T)

mp

202-206 °C (dec.)

storage temp.

2-8°C

Storage Class

13 - Non Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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DNA duplexes are stabilized by many interactions, one of which is stacking interactions between the nucleic acid bases. These interactions are useful for designing small molecules that bind to DNA. Naphthalimide intercalators have been shown to be valuable anti-cancer agents
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Atrophic fracture nonunion poses a significant clinical problem with limited therapeutic interventions. In this study, we developed a unique nonunion model with high clinical relevance using serum transfer-induced rheumatoid arthritis (RA). Arthritic mice displayed fracture nonunion with the absence of

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