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Merck
CN

02750

Sigma-Aldrich

Diethyl (ethoxymethylene)malonate

purum, ≥99.0% (GC)

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About This Item

Linear Formula:
C2H5OCH=C(COOC2H5)2
CAS Number:
Molecular Weight:
216.23
Beilstein:
880058
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
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grade

purum

Assay

≥99.0% (GC)

refractive index

n20/D 1.463

bp

279-283 °C (lit.)

density

1.080 g/mL at 20 °C (lit.)

SMILES string

CCO\C=C(\C(=O)OCC)C(=O)OCC

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Pictograms

Exclamation markEnvironment

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1A

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

291.2 °F - closed cup

Flash Point(C)

144 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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J Girón et al.
Analytical biochemistry, 206(1), 155-160 (1992-10-01)
A recently reported methodology for amino acid analysis by HPLC has been adapted for quantification of N-epsilon-(2-propenal)lysine (a modified lysine by reaction with malondialdehyde that has been found in enzymatic digests of foods and in urine) in biological samples. We
Riin Rebane et al.
The Analyst, 136(24), 5241-5246 (2011-10-26)
A simple method to identify and determine Selenomethionine (SeMet) and Selenomethylselenocysteine (Se-MeSeCys) with diethyl ethoxymethylenemalonate (DEEMM) derivatization and LC-ESI-MS/MS determination was developed. Separation of SeMet and Se-MeSeCys was achieved in 15.3 minutes. The calibration graph was linear in the range
T Nishihata et al.
Journal of pharmacobio-dynamics, 7(9), 607-613 (1984-09-01)
Diethylethoxymethylene malonate (DEEMM) and diethyl maleate (DEM) enhanced the rectal absorption of cefmetazole in rats when studies were carried out using in vivo, in situ rectal loop and in vitro rectal everted sac method. Since an increase of cefmetazole transport
Sergio Gómez-Alonso et al.
Journal of agricultural and food chemistry, 55(3), 608-613 (2007-02-01)
A method has been developed for the simultaneous analysis of biogenic amines, amino acids, and the ammonium ion in wine and beer. Aminoenones formed by the reaction of amino acids, biogenic amines, and the ammonium ion with the derivatization reagent
Benoit Bach et al.
Analytica chimica acta, 732, 114-119 (2012-06-13)
This paper reports on the development of an optimized method for the simultaneous analysis of eight biogenic amines (histamine, methylamine, ethylamine, tyramine, putrescine, cadaverine, phenethylamine, and isoamylamine). The analytical method thus proposed has the following advantages: the easy derivatization of

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