03788
Boc-PNA-T-OH
purum, ≥95.0% (HPLC)
Synonym(s):
N-[2-(Boc-amino)ethyl]-N-(thymin-1-ylacetyl)glycine
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About This Item
Empirical Formula (Hill Notation):
C16H24N4O7
CAS Number:
Molecular Weight:
384.38
UNSPSC Code:
12352200
MDL number:
SMILES string
CC1=CN(CC(=O)N(CCNC(=O)OC(C)(C)C)CC(O)=O)C(=O)NC1=O
grade
purum
assay
≥95.0% (HPLC)
Other Notes
Building block for the synthesis of PNA′s, Peptide Nucleic Acids; Preparation of Dts protected derivative
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T Koch et al.
The journal of peptide research : official journal of the American Peptide Society, 49(1), 80-88 (1997-01-01)
An optimized automated PNA synthesis protocol is reported. Under optimal conditions the product yield of a test 17-mer PNA is approximately 90%. The average coupling yield is 99.4%. The synthesis strategy is Boc/Z and the deprotected amine is neutralized in
M. Planas et al.
The Journal of Organic Chemistry, 64, 7281-7281 (1999)
O. Seitz
Tetrahedron Letters, 40, 4161-4161 (1999)
O. Seitz et al.
Angewandte Chemie (International Edition in English), 111, 2340-2340 (1999)
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