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Merck
CN

06054

Sigma-Aldrich

L-Isoserine

≥98.0% (TLC)

Synonym(s):

(S)-2-Hydroxy-β-alanine, (S)-3-Amino-2-hydroxypropionic acid

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About This Item

Empirical Formula (Hill Notation):
C3H7NO3
CAS Number:
Molecular Weight:
105.09
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.22
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Quality Level

Assay

≥98.0% (TLC)

form

powder

reaction suitability

reaction type: solution phase peptide synthesis

color

white to off-white

mp

197-198 °C

application(s)

peptide synthesis

SMILES string

NC[C@H](O)C(O)=O

InChI

1S/C3H7NO3/c4-1-2(5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1

InChI key

BMYNFMYTOJXKLE-REOHCLBHSA-N

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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The Journal of organic chemistry, 69(16), 5486-5489 (2004-08-04)
A novel and efficient enantioselective synthesis of both enantiomers of syn-(3-trifluoromethyl)isoserine was achieved. Ring opening of trifluoromethylated cyclic sulfates 3, derived from enantiopure trifluoromethylated vicinal diols 2, with various nucleophiles occurred exclusively at C2 with inversion of chirality. Treatment of
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Chemical communications (Cambridge, England), (15)(15), 1630-1631 (2002-08-13)
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The selectin-leukocyte interaction is the initial event in the early inflammatory cascade. This interplay proceeds via the terminal tetrasaccharide sialyl Lewis(x) (sLe(x)), present on physiological selectin ligands and E- and P-selectins located on the endothelial surface. Blocking this process is
B S Coller et al.
The Journal of biological chemistry, 268(28), 20741-20743 (1993-10-05)
Peptides containing sequences derived from the new NH2 terminus of the seven-transmembrane domain thrombin receptor after thrombin cleavage can activate platelets directly. We recently demonstrated that such peptides are readily cleaved and inactivated by plasma, serum, and endothelial cell-associated aminopeptidase

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