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06231

Aluminum chloride hexahydrate

tested according to Ph. Eur.

Synonym(s):

Aluminii chloridum hexahydricum

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About This Item

Empirical Formula (Hill Notation):
AlCl3 · 6H2O
CAS Number:
7784-13-6
Molecular Weight:
241.43
UNSPSC Code:
12352300
PubChem Substance ID:
329748222
EC Number:
231-208-1
MDL number:
MFCD00149134
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agency

USP/NF, tested according to Ph. Eur.

vapor pressure

1 mmHg ( 100 °C)

reaction suitability

reagent type: catalyst
core: aluminum

solubility

H2O: soluble 1gm in 0.9ml, alcohol: soluble 1 gm in 4 ml, diethyl ether: soluble, glycerol: soluble, propylene glycol: soluble

SMILES string

Cl[Al](Cl)Cl.O.O.O.O.O.O

InChI

1S/Al.3ClH.6H2O/h;3*1H;6*1H2/q+3;;;;;;;;;/p-3

InChI key

JGDITNMASUZKPW-UHFFFAOYSA-K

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Application

Aluminum chloride hexahydrate has been used to prepare aluminum maltol and to study its toxicity in rabbits.

Biochem/physiol Actions

Aluminum chloride hexahydrate possess antimicrobial activity, when used in an aqueous form in an antiperspirant formulation. Aluminum chloride can stimulate neurofibrillary changes in neurons of spinal cord and cerebrum in the developing rabbit′s brain.

Preparation Note

1 gm of aluminum chloride hexahydrate dissolves in 0.9 ml water and 4 ml of alcohol. It is also soluble in glycerol, ether and propylene glycol.

pictograms

Health hazardCorrosion
GHS08,GHS05

signalword

Danger

hcodes

H314,H372

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B - STOT RE 1

target_organs

Lungs

supp_hazards

EUH071

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
BCBS0626V
BCBR6014V

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H M Wisniewski et al.
Annals of neurology, 8(5), 479-490 (1980-11-01)
Aluminum chloride injected into the brains of developing rabbits produced profound neurofibrillary changes to neurons of spinal cord and cerebrum similar to those produced in adult rabbits, along with a variety of clinical symptoms with the exception of seizures. Approximately
E Hölzle et al.
Archives of dermatological research, 272(3-4), 321-329 (1982-01-01)
To document deodorant efficacy the antimicrobial activity of a gelatinous antiperspirant formulation of aqueous aluminum chloride hexahydrate was investigated. In vitro assays demonstrated highly bactericidal activity on microorganisms comprising the resident axillary skin flora, including micrococcaceae and aerobic diphtheroid bacteria.
R L Bertholf et al.
Toxicology and applied pharmacology, 98(1), 58-74 (1989-03-15)
We studied the toxicity of an intravenously injected, water-soluble aluminum complex (aluminum maltol) in 20 young adult male New Zealand white rabbits over a period of 8 to 30 weeks. Sixteen rabbits injected with aluminum-free maltol and 15 untreated rabbits
Dragana M Vucić et al.
Acta poloniae pharmaceutica, 70(6), 1021-1026 (2014-01-05)
Antibacterial and antioxidant activity, total phenolic and flavonoid concentrations of aqueous, ethanol and ethyl acetate extracts from the leaves and flowers of Erica herbacea L. were studied. In vitro antibacterial activity of the extracts was determined by macrodilution method. Minimum
Syed Husain Mustafa Rizvi et al.
PloS one, 9(5), e98409-e98409 (2014-06-01)
Aluminium (Al) is the third most abundant element in the earth's crust and its compounds are used in the form of house hold utensils, medicines and in antiperspirant etc. Increasing number of evidences suggest the involvement of Al+3 ions in
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Global Trade Item Number

SKUGTIN
06231-1KG04061826714294

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