07253
(±)-α-Amino-γ-butyrolactone hydrobromide
purum, ≥97.0% (AT)
Synonym(s):
DL-Homoserine lactone hydrobromide
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About This Item
Empirical Formula (Hill Notation):
C4H7NO2 · HBr
CAS Number:
Molecular Weight:
182.02
EC Number:
228-614-6
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
4530084
MDL number:
InChI key
MKLNTBLOABOJFZ-UHFFFAOYSA-N
InChI
1S/C4H7NO2.BrH/c5-3-1-2-7-4(3)6;/h3H,1-2,5H2;1H
SMILES string
Br[H].NC1CCOC1=O
grade
purum
assay
≥97.0% (AT)
mp
220-225 °C (lit.)
application(s)
peptide synthesis
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Steven E A Christiaen et al.
Journal of microbiological methods, 87(2), 213-219 (2011-08-23)
A large number of Gram-negative pathogens produce N-acylhomoserine lactones (AHLs) as signal molecules for quorum sensing (QS). This cell-cell communication system allows them to coordinate gene expression and regulate virulence. Therefore, strategies to inhibit QS are promising for the control
Sandrine Ghirardi et al.
Microbial ecology, 64(3), 725-737 (2012-05-12)
Rhizosphere competence of fluorescent pseudomonads is a prerequisite for the expression of their beneficial effects on plant growth and health. To date, knowledge on bacterial traits involved in rhizosphere competence is fragmented and derived mostly from studies with model strains.
Cheng-Siang Wong et al.
World journal of microbiology & biotechnology, 28(2), 453-461 (2012-07-19)
A chemically defined medium called KGm medium was used to isolate from a sample of sea water a bacterial strain, MW3A, capable of using N-3-oxohexanoyl-L: -homoserine lactone as the sole carbon source. MW3A was clustered closely to Pseudomonas aeruginosa by
Mijin Kim et al.
Water science and technology : a journal of the International Association on Water Pollution Research, 66(7), 1424-1430 (2012-08-07)
Biofouling control by quorum sensing (QS) inhibition and the influence of membrane surface characteristics on biofilm formation and QS inhibition were investigated. Pseudomonas putida isolated from the bio-fouled reverse osmosis (RO) membranes in a real plant was used. Acylase was
Amanda L May et al.
Analytical chemistry, 84(3), 1243-1252 (2012-01-13)
A range of acylhomoserine lactones (AHLs) are used as intraspecies quorum sensing signals by Gram-negative bacteria, and the detection and quantitation of these molecules is of interest. This manuscript reports a liquid chromatographic-isotope dilution tandem mass spectrometric method for the
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