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Merck
CN

07369

trans-1,2-Cyclohexanedicarboxylic anhydride

analytical standard

Synonym(s):

trans-Cyclohexane-1,2-dicarboxylic acid anhydride, trans-Hexahydro-1,3-isobenzofurandione, trans-Hexahydrophthalic anhydride

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About This Item

Empirical Formula (Hill Notation):
C8H10O3
CAS Number:
14166-21-3
Molecular Weight:
154.16
NACRES:
NA.24
PubChem Substance ID:
329748417
UNSPSC Code:
12352200
EC Number:
238-009-9
MDL number:
MFCD00064345

Key Documents

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InChI key

MUTGBJKUEZFXGO-WDSKDSINSA-N

InChI

1S/C8H10O3/c9-7-5-3-1-2-4-6(5)8(10)11-7/h5-6H,1-4H2/t5-,6-/m0/s1

SMILES string

O=C1OC(=O)[C@H]2CCCC[C@H]12

grade

analytical standard

assay

≥97.0% (GC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

145-147 °C (lit.)

application(s)

environmental

storage temp.

2-8°C

Quality Level

100

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General description

This compound is listed in the SVHC (Substances of very high concern) candidate list of ECHA (European Chemicals Agency)

pictograms

Health hazardCorrosion
GHS08,GHS05

signalword

Danger

Hazard Classifications

Eye Dam. 1 - Resp. Sens. 1 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCBR4642V
BCBR4642

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Sol Fereres et al.
PloS one, 9(11), e113255-e113255 (2014-11-22)
Chromatin dependent activation and repression of transcription is regulated by the histone modifying enzymatic activities of the trithorax (trxG) and Polycomb (PcG) proteins. To investigate the mechanisms underlying their mutual antagonistic activities we analyzed the function of Drosophila dRYBP, a
Relja Popovic et al.
PLoS genetics, 10(9), e1004566-e1004566 (2014-09-05)
Overexpression of the histone methyltransferase MMSET in t(4;14)+ multiple myeloma patients is believed to be the driving factor in the pathogenesis of this subtype of myeloma. MMSET catalyzes dimethylation of lysine 36 on histone H3 (H3K36me2), and its overexpression causes

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