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Merck
CN

07551

Vanillylidenacetone

≥98.5%

Synonym(s):

4-(4-Hydroxy-3-methoxyphenyl)-3-buten-2-one

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About This Item

Empirical Formula (Hill Notation):
C11H12O3
CAS Number:
Molecular Weight:
192.21
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
214-096-9
MDL number:
Assay:
≥98.5%
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InChI

1S/C11H12O3/c1-8(12)3-4-9-5-6-10(13)11(7-9)14-2/h3-7,13H,1-2H3/b4-3+

InChI key

AFWKBSMFXWNGRE-ONEGZZNKSA-N

SMILES string

COc1cc(\C=C\C(C)=O)ccc1O

assay

≥98.5%

color

yellow

mp

125-130 °C

functional group

ketone

Quality Level

Gene Information

human ... APP(351)

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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I Rahath Kubra et al.
Journal of food science, 78(1), M64-M69 (2013-01-03)
The efficacy of Dehydrozingerone (DZ; dehydroderivative of zingerone) as an antifungal agent and its mode of action against food spoilage fungal pathogens was studied and presented. DZ is a constituent of ginger (Zingiber officinale rhizomes) and structural half analogue of
Mallikarjuna C Rao et al.
Molecular and cellular biochemistry, 355(1-2), 249-256 (2011-05-14)
Oxidative stress is triggered by the wound which results in the production of reactive oxygen species (ROS), thereby delaying normal wound repair. Therefore, it is important to reduce the level of ROS to improve healing. A known antioxidant, dehydrozingerone (DHZ)
B N Wu et al.
General pharmacology, 25(4), 651-659 (1994-07-01)
1. Dehydrozingeronolol (DZPN; 0.1, 0.5, 1.0 mg/kg, i.v.) produced a dose-dependent bradycardia response and a sustained pressor action in urethane-anesthetized normotensive rats. DZPN inhibited the tachycardia effects by (-)isoproterenol, but had no blocking effect on the arterial pressor responses induced
N Motohashi et al.
Mutation research, 377(1), 17-25 (1997-06-09)
Antimutagenic activities of dehydrozingerone, benzalacetone and its analogs substituted with the hydroxyl, methoxyl or methyl group on the benzene ring were investigated by the post-treatment for UV-induced mutagenesis in Escherichia coli WP2s (uvrA). In this assay, dehydrozingerone was a poor
M Rao et al.
Journal of biochemistry, 125(2), 383-390 (1999-02-17)
We have investigated the effect of phenolic antioxidants on cisplatin-induced cytotoxicity in vero (African Green Monkey Kidney) cells and in rat renal cortical slices in vitro, and on cisplatin-induced nephrotoxicity in rats in vivo. Incubation of cisplatin with vero cells

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