07635
Puromycin aminonucleoside
≥99.0% (HPLC)
Synonym(s):
3′-Amino-3′-deoxy-N6,N6-dimethyladenosine
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About This Item
Empirical Formula (Hill Notation):
C12H18N6O3
CAS Number:
Molecular Weight:
294.31
EC Number:
200-388-3
UNSPSC Code:
12352200
MDL number:
Beilstein/REAXYS Number:
93902
assay
≥99.0% (HPLC)
solubility
H2O: 50 mg/mL, clear, slightly yellow
mode of action
protein synthesis | interferes
storage temp.
2-8°C
SMILES string
CN(C)c1ncnc2n(cnc12)[C@@H]3O[C@H](CO)[C@H](N)[C@@H]3O
InChI
1S/C12H18N6O3/c1-17(2)10-8-11(15-4-14-10)18(5-16-8)12-9(20)7(13)6(3-19)21-12/h4-7,9,12,19-20H,3,13H2,1-2H3/t6-,7+,9+,12-/m1/s1
InChI key
RYSMHWILUNYBFW-VENHTOENSA-N
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Yiqin Zuo et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 27(1), 174-181 (2011-05-14)
Peroxisome proliferator-activated receptor gamma (PPARγ) agonists have beneficial effects on renal structure and function in models of diabetes and chronic kidney diseases. However, the increased incidence of weight gain and edema potentially limits their usefulness. We studied an acute minimal-change
G N Marinides et al.
Kidney international, 37(2), 749-757 (1990-02-01)
The effects of dietary protein and converting enzyme inhibition (CEI) on chronic puromycin aminonucleoside nephropathy (PAN) were studied. PAN was induced with seven SQ injections of puromycin aminonucleoside 20 mg/kg over 10 weeks in male Sprague-Dawley rats. The rats were
Leyi Gu et al.
Kidney international, 81(5), 458-468 (2011-12-15)
In non-neuronal cells, glutamate is an extracellular signaling mediator. Since podocytes have glutamate-containing vesicles, we sought to determine glutamate receptor presence and action in glomerular cells. The metabotropic glutamate receptors (mGluR) 1, 5, 6, and 8 were found to be
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 124087-10G | 04061838345592 |
| 124087-25G | 04061836825010 |