08280
α-Aminoisobutyric acid
puriss., ≥99.0% (NT)
Synonym(s):
alpha-Aminoisobutyric acid, 2-Methylalanine, Aib
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About This Item
Linear Formula:
(CH3)2C(NH2)COOH
CAS Number:
Molecular Weight:
103.12
EC Number:
200-544-0
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
506496
MDL number:
InChI key
FUOOLUPWFVMBKG-UHFFFAOYSA-N
InChI
1S/C4H9NO2/c1-4(2,5)3(6)7/h5H2,1-2H3,(H,6,7)
SMILES string
CC(C)(N)C(O)=O
grade
puriss.
assay
≥99.0% (NT)
ign. residue
≤0.3%
mp
≥300 °C
application(s)
peptide synthesis
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Yosuke Demizu et al.
Journal of peptide science : an official publication of the European Peptide Society, 18(7), 466-475 (2012-05-24)
A pair of L-leucine (L-Leu) and D-leucine (D-Leu) was incorporated into a-aminoisobutyric acid (Aib) peptide segments. Thedominant conformations of four hexapeptides, Boc-L-Leu-Aib-Aib-Aib-Aib-L-Leu-OMe (1a), Boc-D-Leu-Aib-Aib-Aib-Aib-L-Leu-OMe(1b), Boc-Aib-Aib-L-Leu-L-Leu-Aib-Aib-OMe (2a), and Boc-Aib-Aib-D-Leu-L-Leu-Aib-Aib-OMe (2b), were investigated by IR,¹H NMR, CD spectra, and X-ray crystallographic analysis.
Mengmeng Yu et al.
Journal of plant physiology, 168(15), 1820-1827 (2011-07-27)
It has been known that methyl jasmonate (MeJA) interacts with ethylene to elicit resistance. In green mature tomato fruits (Lycopersicon esculentum cv. Lichun), 0.02mM MeJA increased the activity of 1-aminocyclopropane-1-carboxylate oxidase (ACO), and consequently influenced the last step of ethylene
Oak Z Chi et al.
Journal of the neurological sciences, 301(1-2), 66-70 (2010-11-26)
In cerebral ischemia, transmission by the inhibitory neurotransmitter, γ-aminobutyric acid (GABA) is altered. This study was performed to determine whether blockade of GABA(A) receptor would affect regional cerebral blood flow (rCBF) and blood-brain barrier (BBB) permeability in a focal ischemic
Oak Z Chi et al.
Anesthesia and analgesia, 110(5), 1412-1418 (2010-03-23)
We performed experiments to test whether isoflurane pretreatment produces vascular effects, especially at the levels of arterioles and capillaries affecting regional cerebral blood flow (rCBF), O(2) supply and consumption, or capillary permeability in focal cerebral ischemia. Because inducible nitric oxide
Silvia Carlotto et al.
The journal of physical chemistry. B, 115(44), 13026-13036 (2011-10-06)
In this paper, we address the interpretation of molecular properties of selected singly and doubly spin-labeled peptides from continuous-wave electron spin resonance (cw-ESR) spectroscopy. This study is performed by means of an integrated computational approach that merges a stochastic treatment
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