08357
Glutathione reduced diethyl ester
BioChemika
Synonym(s):
GSH diethyl ester
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About This Item
Empirical Formula (Hill Notation):
C14H25N3O6S
CAS Number:
Molecular Weight:
363.43
UNSPSC Code:
12352202
InChI key
IYXATRBAHYMOQL-UWVGGRQHSA-N
InChI
1S/C14H25N3O6S/c1-3-22-12(19)7-16-13(20)10(8-24)17-11(18)6-5-9(15)14(21)23-4-2/h9-10,24H,3-8,15H2,1-2H3,(H,16,20)(H,17,18)/t9-,10-/m0/s1
product line
BioChemika
storage temp.
2-8°C
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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E J Levy et al.
Proceedings of the National Academy of Sciences of the United States of America, 90(19), 9171-9175 (1993-10-01)
Glutathione monoesters in which the carboxyl group of the glycine residue is esterified were previously found, in contrast to glutathione itself, to be effectively transported into various types of cells and to be converted intracellularly into glutathione. Glutathione monoesters are
P J Thornalley et al.
Biochemical pharmacology, 47(2), 418-420 (1994-01-20)
S-p-Bromobenzylglutathione diethyl ester induced toxicity in the malarial parasite Plasmodium falciparum in infected human red blood cells in culture. The median inhibitory concentration, IC50, was 4.77 +/- 0.12 microM (N = 10) for incorporation of [3H]hypoxanthine in nucleotide synthesis and
Akiko Fukumoto et al.
Investigative ophthalmology & visual science, 51(5), 2450-2458 (2010-01-01)
Compounds regulating intracellular thiol redox status, such as N,N-diacetyl-L-cystine dimethylester (NM(2)), were shown to prolong corneal graft survival in a penetrating keratoplasty (PKP) model. However, the effect of NM(2) on hemangiogenesis and lymphangiogenesis has not been investigated. The effect of
Agata Klejman et al.
Neurochemistry international, 47(1-2), 51-57 (2005-06-30)
The occurrence, nature and prevention of ammonia-induced cell death were assayed in cultured primary cortical neurons from newborn rats. Treatment with 1-10 mM ammonium chloride for 24 or 48 h, dose-dependently decreased neuronal survival (MTT assay) and GSH/GSSG ratio in
H S Minhas et al.
Biochemical pharmacology, 49(10), 1475-1482 (1995-05-17)
The effect of reduced glutathione, reduced glutathione monoethyl ester and reduced glutathione diethyl ester on the cellular concentration of reduced glutathione and cysteine in P388D1 macrophages in vitro, and the cellular and extracellular de-esterification of reduced glutathione esters, was investigated.
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