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08566

(Aminomethyl)polystyrene

Name: (Aminomethyl)polystyrene
Brand: SIAL

200-400 mesh, extent of labeling: ~0.6 mmol/g amine loading

Synonym(s):

AM-polystyrene, Benzylamine polymer-bound, Poly(styrene-co-divinylbenzene), aminomethylated, Poly(styrene-co-vinylbenzylamine-co-divinylbenzene, Polystyrene crosslinked with divinylbenzene, aminomethylated

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About This Item

UNSPSC Code:

12352200

PubChem Substance ID:

329748607

NACRES:

NA.22

MDL number:

MFCD00135579

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reaction suitability

reaction type: Boc solid-phase peptide synthesis

extent of labeling

~0.6 mmol/g amine loading

matrix

crosslinked with 1% DVB

particle size

200-400 mesh

application(s)

peptide synthesis

functional group

amine

storage temp.

2-8°C

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Application

Scavenges acids, acid chlorides, anhydrides, aldehydes and other electrophiles

Other Notes

For solid phase peptide synthesis; For polynucleotide synthesis

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Solid-phase synthesis of polynucleotides. IV. Usage of polystyrene resins for the synthesis of polydeoxyribonucleotides by the phosphostriester method.

K Miyoshi et al.

Nucleic acids research, 8(22), 5507-5517 (1980-11-25)

Contrary to the expectation, the Merrifield polystyrene resin, 2% cross-linked by divinylbenzene, is as efficient as the polyacrylmorpholide resin for the synthesis of polydeoxyribonucleotides using a phosphotriester method. On the Merrifield resin, the tetradecamer, dTpCpGpTpCpApApCpTpGpGpCpTpT, and the hexadecamer, dCpCpApGpTpCpApCpGpApCpGpTpTpGpT, were

The use of an internal reference amino acid for the evaluation of reactions in solid-phase peptide synthesis.

G R Matsueda et al.

Analytical biochemistry, 104(1), 215-227 (1980-05-01)

An improved polystyrene support for solid phase peptide synthesis.

J T Sparrow

The Journal of organic chemistry, 41(8), 1350-1353 (1976-04-16)

Solid phase synthesis of polynucleotides. VI. Further studies on polystyrene copolymers for the solid support.

H Ito et al.

Nucleic acids research, 10(5), 1755-1769 (1982-03-11)

A simple solid phase method for the synthesis of oligodeoxyribonucleotides has been developed using the phosphotriester approach. Mononucleotide coupling units are sequentially added to the polystyrene copolymer with 1% divinylbenzene and two kinds of oligonucleotides, d(CACGACCCCTCCACGT) and d(AACTGGTATTACTGGGCG), are synthesized

M. Mutter et al.

Helvetica Chimica Acta, 67, 2009-2009 (1984)

Global Trade Item Number

SKU	GTIN
294985-170G	04061833020920
294985-170G-EU	04061826604397

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