08930
2-Amino-5-nitrophenol
technical, 90-95% (NT)
Synonym(s):
2-Hydroxy-4-nitroaniline, 3-Hydroxy-4-aminonitrobenzene, 3-Nitro-6-aminophenol, 5-Nitro-2-amino-1-hydroxybenzene, 5-Nitro-2-aminophenol, NSC 7087
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About This Item
Linear Formula:
H2NC6H3(NO2)OH
CAS Number:
Molecular Weight:
154.12
EC Number:
204-503-8
UNSPSC Code:
12352100
MDL number:
Beilstein/REAXYS Number:
972974
grade
technical
assay
90-95% (NT)
mp
198-202 °C (dec.) (lit.)
SMILES string
Nc1ccc(cc1O)[N+]([O-])=O
InChI
1S/C6H6N2O3/c7-5-2-1-4(8(10)11)3-6(5)9/h1-3,9H,7H2
InChI key
DOPJTDJKZNWLRB-UHFFFAOYSA-N
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Application
Reactant for:
- Diazotation and coupling reactions
- Preparation of biologically and pharmacologically active molecules
Regulatory Information
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2-Amino-5-nitrophenol.
IARC monographs on the evaluation of carcinogenic risks to humans, 57, 177-184 (1993-01-01)
F Chen et al.
Cancer letters, 126(1), 67-74 (1998-05-01)
Two hair dye components, carcinogenic 4-nitro-2-aminophenol and 5-nitro-2-aminophenol, induced Cu(II)-dependent DNA cleavage frequently at thymine and guanine residues in DNA fragments obtained from the c-Ha-ras-1 protooncogene. When the p53 tumor suppressor gene was used, 4-nitro-2-aminophenol caused Cu(II)-dependent piperidine-labile sites at
Weixia Zhu et al.
Se pu = Chinese journal of chromatography, 30(9), 870-875 (2013-01-05)
An analytical method was developed for the simultaneous determination of 11 aminophenols in direct and oxidized hair dyes by high performance liquid chromatography (HPLC). The samples were extracted with methanol using sodium bisulfite for anti-oxidation. The purification was carried out
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 135186-1L | 04061838730534 |
| 135186-250ML | 04061838730541 |
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