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Merck
CN

09253

Sigma-Aldrich

Luminol

≥98.0% (HPLC)

Synonym(s):

3-Aminophthalhydrazide, 5-Amino-2,3-dihydro-1,4-phthalazinedione

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About This Item

Empirical Formula (Hill Notation):
C8H7N3O2
CAS Number:
Molecular Weight:
177.16
Beilstein:
383929
EC Number:
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
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Assay

≥98.0% (HPLC)

mp

>300 °C (lit.)

SMILES string

Nc1cccc2C(=O)NNC(=O)c12

InChI

1S/C8H7N3O2/c9-5-3-1-2-4-6(5)8(13)11-10-7(4)12/h1-3H,9H2,(H,10,12)(H,11,13)

InChI key

HWYHZTIRURJOHG-UHFFFAOYSA-N

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Features and Benefits

Used for chemiluminescence analysis of, for example, metal cations, blood, and glucococorticoids.

Analysis Note

luminescence test: Emmax 440 nm (chemiluminescence; in 60 mM K2S2O8, 100 mM K2CO3, pH 11.5; after addition of H2O2)

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Ning Zhang et al.
Nature medicine, 19(4), 500-505 (2013-03-05)
A previous study reported the use of luminol for the detection of myeloperoxidase (MPO) activity using optical imaging in infiltrating neutrophils under inflammatory disease conditions. The detection is based on a photon-emitting reaction between luminol and an MPO metabolite. Because
Olga Bloch et al.
Rheumatology (Oxford, England), 53(6), 1034-1042 (2014-02-07)
The activities of two mitogen-activated protein kinases (MAPKs), extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK), correlate with disease severity in SLE patients. Whether they are also associated with long-term organ damage is unknown. The aim of the present
L Huang et al.
Current medicinal chemistry, 20(9), 1195-1202 (2013-01-10)
The light sources used in current photodynamic therapy are mainly lasers or light emitting diodes, which are not suitable to treat large-volume tumors and those located in the inner body. To overcome the limitation, we propose an in situ light
Fuan Wang et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 18(50), 16030-16036 (2012-10-20)
The Cu(2+)-dependent ligation DNAzyme is implemented as a biocatalyst for the colorimetric or chemiluminescence detection of Cu(2+) ions, Hg(2+) ions, or cocaine. These sensing platforms are based on the structural tailoring of the sequence of the Cu(2+)-dependent ligation DNAzyme for
Zhen Zou et al.
Nature communications, 5, 3594-3594 (2014-05-08)
The potential for avian influenza H5N1 outbreaks has increased in recent years. Thus, it is paramount to develop novel strategies to alleviate death rates. Here we show that avian influenza A H5N1-infected patients exhibit markedly increased serum levels of angiotensin

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