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Merck
CN

09293

2-(3-Aminopropylamino)ethanol

≥98.0% (GC)

Synonym(s):

N-(2-Hydroxyethyl)trimethylenediamine

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About This Item

Linear Formula:
NH2CH2CH2CH2NHCH2CH2OH
CAS Number:
Molecular Weight:
118.18
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
224-718-0
Beilstein/REAXYS Number:
1734412
MDL number:
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Quality Level

assay

≥98.0% (GC)

refractive index

n20/D 1.486

bp

250-252 °C (lit.)

density

1.007 g/mL at 20 °C (lit.)

SMILES string

NCCCNCCO

InChI

1S/C5H14N2O/c6-2-1-3-7-4-5-8/h7-8H,1-6H2

InChI key

GHKSKVKCKMGRDU-UHFFFAOYSA-N

Gene Information

rat ... Grin2a(24409)

Other Notes

Inhibitor of the mammalian glycogen debranching enzyme; Photographic development accelerator.


pictograms

CorrosionExclamation mark

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

296.6 °F

flash_point_c

147 °C

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Regulatory Information

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Amylo-1,6-glucosidase/4-alpha-glucanotransferase: use of reversible substrate model inhibitors to study the binding and active sites of rabbit muscle debranching enzyme.
B K Gillard et al.
Biochemistry, 16(18), 3978-3987 (1977-09-06)
Panagiotis Mastorakos et al.
Journal of controlled release : official journal of the Controlled Release Society, 262, 37-46 (2017-07-12)
The discovery of powerful genetic targets has spurred clinical development of gene therapy approaches to treat patients with malignant brain tumors. However, lack of success in the clinic has been attributed to the inability of conventional gene vectors to achieve
Stephany Y Tzeng et al.
International journal of nanomedicine, 6, 3309-3322 (2012-01-10)
Biodegradable poly(ester amine) (PEA)-based and poly(amido amine) (PAA)-based nanoparticles were developed for efficient in vitro siRNA delivery to human umbilical vein endothelial cells (HUVECs). They were screened, characterized, and compared with traditionally studied DNA-containing particles. Several of the polymeric nanoparticles