09295
3-Bromopropylamine hydrobromide
purum, ≥98.0% (AT)
Synonym(s):
3-Aminopropyl bromide hydrobromide
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About This Item
Linear Formula:
BrCH2CH2CH2NH2 · HBr
CAS Number:
Molecular Weight:
218.92
EC Number:
225-675-0
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
3906418
MDL number:
grade
purum
assay
≥98.0% (AT)
mp
171-172 °C (lit.), 171-174 °C
SMILES string
Br.NCCCBr
InChI
1S/C3H8BrN.BrH/c4-2-1-3-5;/h1-3,5H2;1H
InChI key
PQIYSSSTRHVOBW-UHFFFAOYSA-N
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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R A Jue et al.
Analytical biochemistry, 210(1), 39-44 (1993-04-01)
A new reagent for the routine identification of cysteine residues during protein sequencing is described. This method employs 3-bromopropylamine to alkylate cysteines in proteins after reduction with dithiothreitol. Upon sequencing of the protein on an Applied Biosystems 477A protein sequencer
R Medda et al.
Biochemistry, 36(9), 2595-2602 (1997-03-04)
The observation that the alkylamines 2-Br-ethylamine and 2-C1-ethylamine and 1,2-diaminoethane, the shortest diamine, are irreversible inhibitors of several copper amine oxidases led to the investigation of the mechanism by which these compounds react with the highly active amine oxidase from
R A Jue et al.
Analytical biochemistry, 221(2), 374-378 (1994-09-01)
We have previously shown that 3-bromopropylamine offers several advantages over other alkylating reagents in the modification and subsequent identification of cysteine residues by protein sequencing. We describe here simple on-sequencer procedures for alkylating cysteines in proteins which employ the reduction
Alexei Pushechnikov et al.
Journal of the American Chemical Society, 131(28), 9767-9779 (2009-06-26)
Herein, we describe the design of high affinity ligands that bind expanded rCUG and rCAG repeat RNAs expressed in myotonic dystrophy type 1 (DM1) and spinocerebellar ataxia type 3. These ligands also inhibit, with nanomolar IC(50) values, the formation of
M W Crankshaw et al.
Current protocols in protein science, Chapter 15, Unit15-Unit15 (2008-04-23)
This unit describes a number of methods for modifying cysteine residues of proteins and peptides by reduction and alkylation procedures. A general procedure for alkylation of cysteine residues in a protein of known size and composition with haloacyl reagents or
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 111805-5G | 04061838699206 |
| 111805-1G | 04061838699190 |
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