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Merck
CN

10861

Sigma-Aldrich

Succinylsulfathiazole

~95% (TLC)

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About This Item

Empirical Formula (Hill Notation):
C13H13N3O5S2
CAS Number:
116-43-8
Molecular Weight:
355.39
Beilstein:
349989
EC Number:
204-141-0
MDL number:
MFCD00022437
UNSPSC Code:
51101500
PubChem Substance ID:
329749197

Key Documents

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Assay

~95% (TLC)

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria

Mode of action

DNA synthesis | interferes
enzyme | inhibits

SMILES string

OC(=O)CCC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2nccs2

InChI

1S/C13H13N3O5S2/c17-11(5-6-12(18)19)15-9-1-3-10(4-2-9)23(20,21)16-13-14-7-8-22-13/h1-4,7-8H,5-6H2,(H,14,16)(H,15,17)(H,18,19)

InChI key

SKVLYVHULOWXTD-UHFFFAOYSA-N

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General description

Chemical structure: sulfonamide

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H317

Precautionary Statements

P280

Hazard Classifications

Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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R L Walzem et al.
The Journal of nutrition, 118(11), 1343-1348 (1988-11-01)
Thiamin absorption and excretion were assessed in rats with severe folate deficiency (FD) by determining the fate of oral 3H-labeled and intravenous 14C-labeled thiamin over a 6-h test period. Thiamin status was evaluated in these same rats by measuring transketolase
Intraperitoneal administration of succinylsulfathiazole and phthalylsulfathiazole; their use in the prophylaxis and treatment of peritonitis.
J P YOUNG et al.
Archives of surgery (Chicago, Ill. : 1920), 53, 182-189 (1946-08-01)
E O Uthus et al.
Biological trace element research, 58(1-2), 25-33 (1997-07-01)
A previous experiment using rats indicated that dietary nickel (Ni), folic acid, and their interaction affected variables associated with one-carbon metabolism. That study used diets that produced only mild folate deficiency. Thus, an experiment was performed to determine the effect
A G Fogg et al.
Journal of clinical pharmacy and therapeutics, 17(2), 107-109 (1992-04-01)
Ethylenediaminetetraacetic acid (EDTA) was shown to be effective in stabilizing pharmaceutical compounds, which contain acetamido groups, from degradation by light, e.g. paracetamol. Its addition is particularly effective in stabilizing such compounds from the action of ascorbic acid in the light
Succinylsulfathiazole in the nutrition of the rat.
L D WRIGHT et al.
The American journal of the medical sciences, 212(3), 312-314 (1946-09-01)
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