10861
Succinylsulfathiazole
~95% (TLC)
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About This Item
Empirical Formula (Hill Notation):
C13H13N3O5S2
CAS Number:
Molecular Weight:
355.39
EC Number:
204-141-0
UNSPSC Code:
51101500
PubChem Substance ID:
Beilstein/REAXYS Number:
349989
MDL number:
InChI key
SKVLYVHULOWXTD-UHFFFAOYSA-N
InChI
1S/C13H13N3O5S2/c17-11(5-6-12(18)19)15-9-1-3-10(4-2-9)23(20,21)16-13-14-7-8-22-13/h1-4,7-8H,5-6H2,(H,14,16)(H,15,17)(H,18,19)
SMILES string
OC(=O)CCC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2nccs2
assay
~95% (TLC)
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria
mode of action
DNA synthesis | interferes, enzyme | inhibits
General description
Chemical structure: sulfonamide
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G M Semchuk et al.
The Journal of nutrition, 124(7), 1118-1125 (1994-07-01)
This study was designed to assess the effect of succinylsulfathiazole on the apparent bioavailability of folate added to milk-containing diets. We also evaluated the impact of milk type on the relative bioavailability (bioavailability) of folate following pasteurization (62.5 degrees C
S W Choi et al.
Gut, 43(1), 93-99 (1998-10-15)
Diminished folate status appears to promote colonic carcinogenesis by, as of yet, undefined mechanisms. Impaired DNA repair plays a significant role in the evolution of many colon cancers. Since folate is essential for the de novo synthesis of nucleotides and
USE OF SULFASUXIDINE IN RESECTION OF CARCINOMA OF THE COLON-EFFECT ON INFECTION AND MORTALITY.
H G Bell
California medicine, 66(5), 292-294 (1947-05-01)
Rodrigue Yossa et al.
Zebrafish, 8(4), 221-227 (2011-10-13)
A study was conducted to preliminarily assess the contribution of the intestinal microflora to biotin supply in zebrafish. Biotin and avidin were added to three isonitrogenous and isocaloric purified diets to provide molar avidin: biotin ratios of 0:0 (basal diet)
Ki-Yeon Yoo et al.
Genes & nutrition, 2(4), 331-336 (2008-10-14)
Folate deficiency increases stroke risk. We examined whether folate deficiency affects platelet endothelial cell adhesion molecule-1 (PECAM-1), which is an immunoglobulin-associated cell adhesion molecule and mediates the final common pathway of neutrophil transendothelial migration, in blood vessels in the gerbil
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