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Merck
CN

11015

D-Arginine

puriss., ≥99.0% (NT)

Synonym(s):

(R)-2-Amino-5-guanidinopentanoic acid

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About This Item

Linear Formula:
H2NC(=NH)NH(CH2)3CH(NH2)CO2H
CAS Number:
Molecular Weight:
174.20
EC Number:
205-866-5
UNSPSC Code:
12352200
eCl@ss:
32160406
Beilstein/REAXYS Number:
1725412
MDL number:
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grade

puriss.

assay

≥99.0% (NT)

optical activity

[α]20/D −26.5±0.5°, c = 5% in 5 M HCl

ign. residue

≤0.05%

loss

~0.5% loss on drying, 20 °C (HV)

mp

226 °C (dec.) (lit.), ~240 °C (dec.)

SMILES string

N[C@H](CCCNC(N)=N)C(O)=O

InChI

1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t4-/m1/s1

InChI key

ODKSFYDXXFIFQN-SCSAIBSYSA-N

Storage Class

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Daniela Melisi et al.
Journal of medicinal chemistry, 49(16), 4826-4833 (2006-08-04)
Nitric oxide (NO) is critical for the normal physiological regulation of the nervous system and other tissues. L-Arginine, but not D-arginine, is the natural substrate for nitric oxide synthase (NOS), for it is enzymatically converted to NO and L-citrulline. However
Claudia E Robert-Cooperman et al.
Diabetes, 59(9), 2209-2218 (2010-06-23)
Pancreatic-derived factor (PANDER, FAM3B) is a pancreatic islet-specific cytokine-like protein that is secreted from beta-cells upon glucose stimulation. The biological function of PANDER is unknown, and to address this we generated and characterized a PANDER knockout mouse. To generate the
Lei Fang et al.
Journal of proteome research, 7(11), 4914-4925 (2008-10-15)
The COP9 signalosome (CSN) is a multiprotein complex that plays a critical role in diverse cellular and developmental processes in various eukaryotic organisms. Despite of its significance, current understanding of the biological functions and regulatory mechanisms of the CSN complex

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