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Merck
CN

114472

Cresol red

indicator grade, Dye content 95 %

Synonym(s):

o-Cresolsulfonphthalein

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About This Item

Empirical Formula (Hill Notation):
C21H18O5S
CAS Number:
1733-12-6
Molecular Weight:
382.43
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
24847173
EC Number:
217-064-2
Beilstein/REAXYS Number:
343399
MDL number:
MFCD00005878

Key Documents

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InChI key

OBRMNDMBJQTZHV-UHFFFAOYSA-N

InChI

1S/C21H18O5S/c1-13-11-15(7-9-18(13)22)21(16-8-10-19(23)14(2)12-16)17-5-3-4-6-20(17)27(24,25)26-21/h3-12,22-23H,1-2H3

SMILES string

Cc1cc(ccc1O)C2(OS(=O)(=O)c3ccccc23)c4ccc(O)c(C)c4

grade

indicator grade

form

powder or crystals

composition

Dye content, 95%

technique(s)

titration: suitable

color

red-brown

pH

7.2-8.8, yellow to red

useful pH range

1.8-2.0, orange to yellow(acid), 7.0-8.8, yellow to violet(alkaline)

mp

290 °C

density

0.998 g/cm3

λmax

367 nm (2nd), 570 nm

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

Quality Level

200

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General description

Cresol Red, also known as o-cresol red, belongs to the phthalein and sulphonphthalein group of dyes. Cresol red changes color from orange to yellow at pH between 0.2-1.8 and yellow to violet at pH between 7.0-8.8. In alkaline solutions, cresol red is present as a hydrophilic dianion. The dianion is small and is violet in color, possessing a larger conjugated system than the yellow hydroxyquinone.

Application

Cresol Red is a widely used pH indicator for routine pH assessments like microbial culture media preparations. In addition, Cresol red is a suitable constituent of PCR reagent systems. Cresol Red is used as a tracking dye in DNA, RNA (agarose), and protein (polyacrylamide) electrophoresis.

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN5450
BCCL9070
BCCJ9752
BCCH4332
BCCG0571

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Atsushi Seki et al.
Analytica chimica acta, 582(1), 154-157 (2007-03-28)
Novel spectroscopic sensor based on a hetero-core structured fiber optic is described in this paper. The hetero-core structured fiber optic consists of multi mode fibers and a short piece of single mode fiber which was inserted in the multi mode
H N Nigg et al.
Journal of economic entomology, 97(6), 1850-1860 (2005-01-26)
We needed a technique to compare the consumption of baits by individual Carribbean fruit fly, Anastrepha suspensa (Loew). By improving consumption and determining individual dose, we could lower pesticide concentration while retaining bait/pesticide efficacy and potentially reduce the environmental impact
K Elamrani et al.
Biochimica et biophysica acta, 727(1), 22-30 (1983-01-05)
The kinetics of H+/OH- diffusion across dimyristoyl phosphatidic acid bilayer membranes was measured by following the absorbance of the pH-sensitive indicator Cresol red (o-cresolsulfonphthalein) entrapped in single lamellar vesicles after rapidly changing the external pH in a stopped-flow apparatus. The
K Schilling et al.
Clinical chemistry, 39(2), 251-256 (1993-02-01)
If buffer/indicator systems are used as optical thermometers in multicuvettes, the temperature resolution is limited by errors of optical measurements produced mainly by variations of pathlength and blank transmittance of the wells. Theoretical and practical approaches show that, in multicuvettes
M Swati et al.
Analytica chimica acta, 676(1-2), 68-74 (2010-08-31)
An optical biosensing scheme based on urease encapsulated calcium alginate microspheres which are coated with polyelectrolyte nanofilms predominantly composed of cresol red (CR) dye is demonstrated in this paper. The dye molecules within the nanofilms are deposited via the layer-by-layer
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