11545
4-Azidoaniline hydrochloride
≥98.0% (AT)
Synonym(s):
4-Aminophenyl azide hydrochloride
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About This Item
Linear Formula:
N3C6H4NH2 · HCl
CAS Number:
Molecular Weight:
170.60
PubChem Substance ID:
UNSPSC Code:
12352100
Beilstein/REAXYS Number:
7942921
MDL number:
assay
≥98.0% (AT)
mp
165 °C (dec.) (lit.)
solubility
methanol: soluble
SMILES string
Cl.Nc1ccc(cc1)N=[N+]=[N-]
InChI
1S/C6H6N4.ClH/c7-5-1-3-6(4-2-5)9-10-8;/h1-4H,7H2;1H
InChI key
SDYAJRBHPPWHSF-UHFFFAOYSA-N
Application
4-Azidoaniline hydrochloride has been used in the synthesis and preparation of [α-32 P]GTP-azidoanilide (GTP-AA).
Other Notes
Versatile protein and peptide modifying agent for photoaffinity labeling; Photoaffinity labeling of GTP-binding proteins.
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Flam. Sol. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
4.1B - Flammable solid hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Regulatory Information
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Photoaffinity labeling of GTP-binding proteins.
R Thomas et al.
Methods in enzymology, 195, 280-286 (1991-01-01)
Yoshihiro Ito et al.
Acta biomaterialia, 3(6), 1024-1032 (2007-07-24)
Photoreactive poly(ethylene glycol) (PEG) was prepared and the polymer was photoimmobilized on organic, inorganic and metal surfaces to reduce their interaction with proteins and cells. The photoreactive PEG was synthesized by co-polymerization of methacrylate-PEG and acryloyl 4-azidobenzene. Surface modification was
D Stangl et al.
Biochemistry, 30(35), 8605-8611 (1991-09-03)
Calcitonin gene-related peptide (CGRP) receptors were solubilized from human (h) cerebellum with use of the zwitterionic detergent 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonic acid (CHAPS). Scatchard analysis of equilibrium binding data indicated that the soluble extract contained a single class of CGRP binding sites with
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 302538-5G | 04061831810486 |
| 302538-1G | 04061826665923 |