125660
Leucomalachite Green
powder
Synonym(s):
4,4′-Benzylidenebis(N,N-dimethylaniline)
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About This Item
Linear Formula:
C6H5CH[C6H4N(CH3)2]2
CAS Number:
Molecular Weight:
330.47
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
EC Number:
204-961-9
Beilstein/REAXYS Number:
2140506
MDL number:
form
powder
Quality Level
technique(s)
microbe id | staining: suitable
mp
100-102 °C (lit.)
λmax
623 nm
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
SMILES string
CN(C)c1ccc(cc1)C(c2ccccc2)c3ccc(cc3)N(C)C
InChI
1S/C23H26N2/c1-24(2)21-14-10-19(11-15-21)23(18-8-6-5-7-9-18)20-12-16-22(17-13-20)25(3)4/h5-17,23H,1-4H3
InChI key
WZKXBGJNNCGHIC-UHFFFAOYSA-N
Application
Leucomalachite green has been used as a reagent in presumptive tests which are used to detect invisible blood stains.
Biochem/physiol Actions
Leucomalachite green (LMG) is a chief metabolite of malachite green, a triphenylmethane dye that has been used generally as an antifungal drug in the fish industry. DNA adducts formed in livers of rats fed with leucomalachite green have been observed with little mutagenic or carcinogenic effect. LMG is one of the most commonly used reagents for presumptive blood test. It gives a characteristic green color in the presence of blood. LMG destroys DNA in the blood, therefore, the chances of DNA recovery and amplification is reduced or eliminated.
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Muta. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Mutagenicity and carcinogenicity in relation to DNA adduct formation in rats fed leucomalachite green.
Culp SJ
Mutation Research, 506-507, 55-63 (2002)
Evidence of aerosolised floating blood mist during oral surgery.
Ishihama K
Journal of Hospital Infection, 71(4), 359-364 (2009)
Becker, Ronald F. Becker, Aric W. Dutelle
Criminal Investigation (2012)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 125660-5G | 04061838723666 |
| 125660-25G | 04061838723659 |