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Merck
CN

14089

Succinic anhydride

puriss., ≥99.0% (NT)

Synonym(s):

Dihydro-2,5-furandione

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About This Item

Empirical Formula (Hill Notation):
C4H4O3
CAS Number:
Molecular Weight:
100.07
EC Number:
203-570-0
UNSPSC Code:
12162002
PubChem Substance ID:
Beilstein/REAXYS Number:
108441
MDL number:
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InChI key

RINCXYDBBGOEEQ-UHFFFAOYSA-N

InChI

1S/C4H4O3/c5-3-1-2-4(6)7-3/h1-2H2

SMILES string

O=C1CCC(=O)O1

vapor density

3.5 (vs air)

vapor pressure

1 mmHg ( 92 °C)

grade

puriss.

assay

≥99.0% (NT)

bp

261 °C (lit.)

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signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 1

flash_point_f

314.6 °F

flash_point_c

157 °C

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Jean-François Poulin et al.
International journal of pharmaceutics, 405(1-2), 47-54 (2010-12-07)
The use of succinylated β-lactoglobulin as a novel functional tablet excipient for the protection of probiotic bacteria against the adverse gastric conditions and their delivery in the intestine was studied. Tablets were produced by direct compression of a dry mixture
Peisheng Xu et al.
Biomacromolecules, 11(9), 2352-2358 (2010-08-11)
Zwitterionic chitosan, a chitosan derivative with a unique pH-dependent charge profile, was employed to create a stealth coating on the cationic surface of drug carriers. Zwitterionic chitosans were synthesized by amidation of chitosan with succinic anhydride. The succinic anhydride-conjugated chitosan
Bingnan Han et al.
Journal of proteomics, 75(18), 5724-5733 (2012-07-31)
We report a mass spectrometry-based comparative "bottom up" proteomics approach that combines d(0)/d(4)-succinic anhydride labeling with commercially available hydrazine (Hz)-functionalized beads (Affi-gel Hz beads) for detection, identification and relative quantification of site-specific oxylipid modifications in biological matrices. We evaluated and
Yu-Li Lin et al.
PLoS genetics, 5(10), e1000680-e1000680 (2009-10-10)
The p53 family activates many of the same genes in response to DNA damage. Because p63 and p73 have structural differences from p53 and play distinct biological functions in development and metastasis, it is likely that they activate a unique
Margarita D Popova et al.
International journal of pharmaceutics, 436(1-2), 778-785 (2012-08-14)
The present study deals with the development and functionalization of mesoporous silica nanoparticles as drug delivery platforms. Spherical MCM-41 and SBA-15 silicas with different pore sizes (2.7 nm and 5.5 nm, respectively) were post-synthesis modified applying a new, two step

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