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14339

Bicinchoninic acid disodium salt hydrate

≥99.0% (HPLC)

Synonym(s):

2,2′-Biquinoline-4,4′-dicarboxylic acid disodium salt, 4,4′-Dicarboxy-2,2′-biquinoline disodium salt, BCA, Disodium 2,2′-biquinoline-4,4′-dicarboxylate

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About This Item

Empirical Formula (Hill Notation):
C20H10N2Na2O4 · xH2O
CAS Number:
979-88-4
Molecular Weight:
388.28 (anhydrous basis)
UNSPSC Code:
12171500
PubChem Substance ID:
329750454
MDL number:
MFCD10567219
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assay

≥99.0% (HPLC)

impurities

~12% water

SMILES string

O.[Na+].[Na+].[O-]C(=O)c1cc(nc2ccccc12)-c3cc(C([O-])=O)c4ccccc4n3

InChI

1S/C20H12N2O4.2Na.H2O/c23-19(24)13-9-17(21-15-7-3-1-5-11(13)15)18-10-14(20(25)26)12-6-2-4-8-16(12)22-18;;;/h1-10H,(H,23,24)(H,25,26);;;1H2/q;2*+1;/p-2

InChI key

FAFVGCAYKZKOPT-UHFFFAOYSA-L

Other Notes

Photometric reagent for protein assay. Forms an intense purple complex with the cuprous ion and hence the basis of the analytical monitoring of cuprous ion produced in the biuret reaction. Demonstrates greater tolerance to interference from non-ionic detergents and simple buffer salts

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pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Regulatory Information

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C.S. Chang et al.
Proceedings of the National Academy of Sciences of the USA, 83, 100-100 (1985)
M G Redinbaugh et al.
Analytical biochemistry, 153(2), 267-271 (1986-03-01)
The bincinchoninic acid protein assay has been adapted for use with microtiter plates and a plate reader to reduce the time needed for analyses. The total volume of the assay was reduced to 0.21 ml with various ratios of sample
Martha Lappas
PloS one, 9(12), e115854-e115854 (2014-12-30)
Infection and inflammation, through their ability to increase pro-inflammatory cytokines and chemokines and adhesion molecules, are thought to play a central role in the pathophysiology of insulin resistance and type 2 diabetes. Recent studies have shown that glycogen synthase kinase
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