14872
BICINE
≥99.0% (T)
Synonym(s):
N,N-Bis(2-hydroxyethyl)glycine
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About This Item
Empirical Formula (Hill Notation):
C6H13NO4
CAS Number:
Molecular Weight:
163.17
EC Number:
205-755-1
UNSPSC Code:
12161700
MDL number:
Beilstein/REAXYS Number:
1769362
assay
≥99.0% (T)
ign. residue
≤0.5%
loss
≤0.5% loss on drying, 20 °C (HV)
useful pH range
7.6-9.0
pKa (20 °C)
8.3
pKa (25 °C)
8.3
solubility
H2O: 0.1 g/mL at 20 °C, clear
anion traces
chloride (Cl-): ≤500 mg/kg, sulfate (SO42-): ≤50 mg/kg
cation traces
Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg
SMILES string
OCCN(CCO)CC(O)=O
InChI
1S/C6H13NO4/c8-3-1-7(2-4-9)5-6(10)11/h8-9H,1-5H2,(H,10,11)
InChI key
FSVCELGFZIQNCK-UHFFFAOYSA-N
Application
Recommended buffer for low temperature biochemical work. Used in the preparation of stable substrate solution for serum guanase determination. Spacer in plasma protein fractionation with Sephadex® by isotachophoresis.
Legal Information
Sephadex is a registered trademark of Cytiva
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S Ito et al.
The Histochemical journal, 16(5), 489-499 (1984-05-01)
Histochemical studies of human guanase (guanine deaminase) have seldom been undertaken, in part because of technical difficulties which result in heavy background staining. In this report, we describe a modified procedure in which the methodological inadequacies have been overcome. The
R N Roy et al.
Cryobiology, 21(6), 672-681 (1984-12-01)
The establishment of the pH (designated pH*) of a standard buffer solution suitable as a pH reference in 30, 40, and 50 mass% dimethyl sulfoxide (DMSO)/H2O mixtures at temperatures in the range -20 to 0 degrees C is reported. The
Yoshiteru Seo et al.
Magnetic resonance in medicine, 65(4), 1005-1012 (2011-03-18)
The toxicity of free Mn(2+) is a bottleneck for the in vivo application of manganese ion enhanced MRI. To reduce free Mn(2+) concentration ([Mn(2+) ]), a low affinity chelate reagent: N,N-bis(2-hydroxyethyl)glycine (bicine) was used. Considering the conditional association constant of