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Merck
CN

15940

Pyruvic acid

purum, ≥98.0% (T)

Synonym(s):

α-Ketopropionic acid, 2-Oxopropionic acid

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About This Item

Linear Formula:
CH3COCOOH
CAS Number:
127-17-3
Molecular Weight:
88.06
EC Number:
204-824-3
UNSPSC Code:
12352100
PubChem Substance ID:
24849813
Beilstein/REAXYS Number:
506211
MDL number:
MFCD00002585
eCl@ss:
39021320

Key Documents

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grade

purum

assay

≥98.0% (T)

refractive index

n20/D 1.428 (lit.), n20/D 1.429

bp

165 °C (lit.)

mp

11-12 °C (lit.)

density

1.268 g/mL at 20 °C, 1.267 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

CC(=O)C(O)=O

InChI

1S/C3H4O3/c1-2(4)3(5)6/h1H3,(H,5,6)

InChI key

LCTONWCANYUPML-UHFFFAOYSA-N

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General description

Pyruvic acid is an α-keto-carboxylic acid. It is an metabolic intermediate and is a building unit for many biological compounds. Determination of pyruvic acid in blood and urine samples has been repoted.

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H314

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1C

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 1

flash_point_f

183.2 °F - closed cup

flash_point_c

84 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

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Christian Henning et al.
The Journal of biological chemistry, 289(41), 28676-28688 (2014-08-29)
Maillard α-dicarbonyl compounds are known as central intermediates in advanced glycation end product (AGE) formation. Glucose is the primary source of energy for the human body, whereas l-threo-ascorbic acid (vitamin C) is an essential nutrient, involved in a variety of
Pyruvic acid. II. The determination of keto acids in blood and urine.
Friedemann TE and Haugen GE.
The Journal of Biological Chemistry, 147(415), 943-943 (1943)
Pyruvic acid, a unique component of an exocellular bacterial polysaccharide.
J H SLONEKER et al.
Nature, 194, 478-479 (1962-05-05)
Sarah C Atkinson et al.
Plant molecular biology, 81(4-5), 431-446 (2013-01-29)
Lysine is one of the most limiting amino acids in plants and its biosynthesis is carefully regulated through inhibition of the first committed step in the pathway catalyzed by dihydrodipicolinate synthase (DHDPS). This is mediated via a feedback mechanism involving
Emilie A Bard-Chapeau et al.
Nature genetics, 46(1), 24-32 (2013-12-10)
The most common risk factor for developing hepatocellular carcinoma (HCC) is chronic infection with hepatitis B virus (HBV). To better understand the evolutionary forces driving HCC, we performed a near-saturating transposon mutagenesis screen in a mouse HBV model of HCC.
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