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Merck
CN

17385

4-Fluoro-7-sulfamoylbenzofurazan

Synonym(s):

4-(Aminosulfonyl)-7-fluorobenzofurazane, 7-Fluoro-2,1,3-benzoxadiazole-4-sulfonamide, 7-Fluorobenzofurazan-4-sulfonamide, ABD-F

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About This Item

Empirical Formula (Hill Notation):
C6H4FN3O3S
CAS Number:
Molecular Weight:
217.18
UNSPSC Code:
12352200
Beilstein/REAXYS Number:
5035147
MDL number:
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solubility

DMSO: soluble, acetonitrile: soluble

fluorescence

λex 375 nm; λem 521 nm (after derivatization with 2-mercaptoethanol)

suitability

suitable for fluorescence

storage temp.

−20°C

SMILES string

NS(=O)(=O)c1ccc(F)c2nonc12

InChI

1S/C6H4FN3O3S/c7-3-1-2-4(14(8,11)12)6-5(3)9-13-10-6/h1-2H,(H2,8,11,12)

InChI key

XROXHZMRDABMHS-UHFFFAOYSA-N

Other Notes

Fluorogenic reagent for the labeling of thiols for HPLC; it reacts 30 times faster than SBD-F

Regulatory Information

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Isolation and characterization of cysteine-containing regions of proteins using 4-(aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole and high-performance liquid chromatography.
T Toyo'oka et al.
Analytical chemistry, 57(9), 1931-1937 (1985-08-01)
Toyooka, T. and Imai, K.
Analytical Chemistry, 56, 2461-2461 (1984)

Global Trade Item Number

SKUGTIN
H3916-10MG04061838450432

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