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177539

Syringaldazine

98%, powder or crystals

Synonym(s):

4-Hydroxy-3,5-dimethoxybenzaldehyde azine

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About This Item

Linear Formula:
[HOC6H2(OCH3)2CH=N-]2
CAS Number:
14414-32-5
Molecular Weight:
360.36
NACRES:
NA.83
PubChem Substance ID:
329751558
UNSPSC Code:
12352204
EC Number:
238-390-1
MDL number:
MFCD00008363
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Product Name

Syringaldazine, 98%

Quality Level

100

assay

98%

form

powder or crystals

mp

209-210 °C (lit.)

solubility

DMF: 5%, clear to hazy

storage temp.

2-8°C

SMILES string

COc1cc(\C=N\N=C\c2cc(OC)c(O)c(OC)c2)cc(OC)c1O

InChI

1S/C18H20N2O6/c1-23-13-5-11(6-14(24-2)17(13)21)9-19-20-10-12-7-15(25-3)18(22)16(8-12)26-4/h5-10,21-22H,1-4H3/b19-9+,20-10+

InChI key

YARKTHNUMGKMGS-LQGKIZFRSA-N

Application

Syringaldazine has been used as a substrate to measure the enzymatic activity of recombinant laccase.

Biochem/physiol Actions

Syringaldazine (4-Hydroxy-3, 5-dimethoxybenzaldehyde azine) is a nonautooxidizable laccase-specific compound. It acts as a substrate for laccase and peroxidase in the presence of hydrogen peroxide (H2O2). Syringaldazine also acts as an electron donor in the prostaglandin H synthase (PGHS) reaction.

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pictograms

Flame
GHS02

signalword

Warning

hcodes

H228

pcodes

P210

Hazard Classifications

Flam. Sol. 2

Storage Class

4.1B - Flammable solid hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCK2256
BCCH9948
BCCG4241
STBJ7683
STBJ3050

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Use of syringaldazine for detection of laccase in sporophores of wood rotting fungi.
J M Harkin et al.
Mycologia, 66(3), 469-476 (1974-05-01)
W Bao et al.
Science (New York, N.Y.), 260(5108), 672-674 (1993-04-30)
Peroxidase has been thought to be the only enzyme that oxidizes monolignol precursors to initiate lignin formation in plants. A laccase was purified from cell walls of differentiating xylem of loblolly pine and shown to coincide in time and place
Y A Kuznetsova et al.
Applied biochemistry and biotechnology, 61(1-2), 205-209 (1996-10-01)
The prostaglandin H synthase (PGHS) reaction has been studied with syringaldazine as the electron donor. Kinetic parameters of the reaction agreed with those for commonly used electron donors. The sensitivity of the PGHS activity detection in the presence of syringaldazine
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Global Trade Item Number

SKUGTIN
177539-1G04061835514915