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Merck
CN

18493

MUG Supplement

suitable for microbiology

Synonym(s):

4-Methylumbelliferyl-β-D-glucuronide, 4-Methylumbelliferyl-β-D-glucuronide Supplement, MUGlcU

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About This Item

Empirical Formula (Hill Notation):
C16H16O9
CAS Number:
Molecular Weight:
352.29
NACRES:
NA.85
PubChem Substance ID:
UNSPSC Code:
41171614
EC Number:
228-186-0
MDL number:
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InChI

1S/C16H16O9/c1-6-4-10(17)24-9-5-7(2-3-8(6)9)23-16-13(20)11(18)12(19)14(25-16)15(21)22/h2-5,11-14,16,18-20H,1H3,(H,21,22)/t11-,12-,13+,14-,16+/m0/s1

InChI key

ARQXEQLMMNGFDU-JHZZJYKESA-N

SMILES string

O[C@@H]1[C@@H](O)[C@H](O)[C@@H](C(O)=O)O[C@H]1OC2=CC(OC(C=C3C)=O)=C3C=C2

sterility

sterile

form

powder

shelf life

limited shelf life, expiry date on the label

application(s)

agriculture
environmental
food and beverages, microbiology

storage temp.

2-8°C

suitability

Escherichia coli, coliforms

Quality Level

Application

Fluorogenic substrate for measuring of β-glucoronidiase activity, for identifiacation of Escherichia coli.

Other Notes

(per vial, sufficient for 500 ml medium)
4-Methylumbelliferyl β-D-glucuronide (MUG) 50.0 mg

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Steven Pao et al.
Journal of food protection, 65(12), 1943-1948 (2002-12-24)
This study was undertaken to investigate interference by acids commonly found in fruit juice in Escherichia coli assays involving the use of 4-methylumbelliferyl-beta-D-glucuronide (MUG) as a fluorogenic substrate for enzyme reaction. Fluorescence intensity was negatively correlated (P < 0.001) with
Misty L Pope et al.
Applied and environmental microbiology, 69(10), 6201-6207 (2003-10-09)
Escherichia coli is a routinely used microbiological indicator of water quality. To determine whether holding time and storage conditions had an effect on E. coli densities in surface water, studies were conducted in three phases, encompassing 24 sites across the
Michael B Tropak et al.
The Journal of biological chemistry, 279(14), 13478-13487 (2004-01-16)
Tay-Sachs and Sandhoff diseases are lysosomal storage disorders that result from an inherited deficiency of beta-hexosaminidase A (alphabeta). Whereas the acute forms are associated with a total absence of hexosaminidase A and early death, the chronic adult forms exist with
Bernhard Sperker et al.
Life sciences, 71(13), 1547-1557 (2002-07-20)
Antibody directed enzyme prodrug therapy (ADEPT) using glucuronide prodrugs is an experimental approach to reduce systemic toxicity of anti-cancer agents. Bioactivation of such prodrugs is achieved by fusion proteins consisting of targeting moieties (e.g. ligands of tumor specific antigens) and
T Garcia-Armisen et al.
Letters in applied microbiology, 40(4), 278-282 (2005-03-09)
The relationships between the beta-D-glucuronidase (GLUase) activity, the abundance of culturable Escherichia coli and the number of viable E. coli were investigated in river and wastewater samples. GLUase activity was measured as the rate of hydrolysis of 4-methylumbelliferyl-beta-D-glucuronide. Culturable E.

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