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Merck
CN

18493

MUG Supplement

suitable for microbiology

Synonym(s):

4-Methylumbelliferyl-β-D-glucuronide, 4-Methylumbelliferyl-β-D-glucuronide Supplement, MUGlcU

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About This Item

Empirical Formula (Hill Notation):
C16H16O9
CAS Number:
6160-80-1
Molecular Weight:
352.29
NACRES:
NA.85
PubChem Substance ID:
329751679
UNSPSC Code:
41171614
EC Number:
228-186-0
MDL number:
MFCD00036772

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InChI

1S/C16H16O9/c1-6-4-10(17)24-9-5-7(2-3-8(6)9)23-16-13(20)11(18)12(19)14(25-16)15(21)22/h2-5,11-14,16,18-20H,1H3,(H,21,22)/t11-,12-,13+,14-,16+/m0/s1

InChI key

ARQXEQLMMNGFDU-JHZZJYKESA-N

SMILES string

O[C@@H]1[C@@H](O)[C@H](O)[C@@H](C(O)=O)O[C@H]1OC2=CC(OC(C=C3C)=O)=C3C=C2

sterility

sterile

form

powder

shelf life

limited shelf life, expiry date on the label

application(s)

agriculture
environmental
food and beverages, microbiology

storage temp.

2-8°C

suitability

Escherichia coli, coliforms

Quality Level

100

Related Categories

Application

Fluorogenic substrate for measuring of β-glucoronidiase activity, for identifiacation of Escherichia coli.

Other Notes

(per vial, sufficient for 500 ml medium)
4-Methylumbelliferyl β-D-glucuronide (MUG) 50.0 mg

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN4558
BCCN0723
BCCM7648
BCCH4341
BCCG4785

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Bernhard Sperker et al.
Life sciences, 71(13), 1547-1557 (2002-07-20)
Antibody directed enzyme prodrug therapy (ADEPT) using glucuronide prodrugs is an experimental approach to reduce systemic toxicity of anti-cancer agents. Bioactivation of such prodrugs is achieved by fusion proteins consisting of targeting moieties (e.g. ligands of tumor specific antigens) and
T Garcia-Armisen et al.
Letters in applied microbiology, 40(4), 278-282 (2005-03-09)
The relationships between the beta-D-glucuronidase (GLUase) activity, the abundance of culturable Escherichia coli and the number of viable E. coli were investigated in river and wastewater samples. GLUase activity was measured as the rate of hydrolysis of 4-methylumbelliferyl-beta-D-glucuronide. Culturable E.
Michael B Tropak et al.
The Journal of biological chemistry, 279(14), 13478-13487 (2004-01-16)
Tay-Sachs and Sandhoff diseases are lysosomal storage disorders that result from an inherited deficiency of beta-hexosaminidase A (alphabeta). Whereas the acute forms are associated with a total absence of hexosaminidase A and early death, the chronic adult forms exist with
S K Manna et al.
Journal of applied microbiology, 108(2), 658-665 (2009-10-03)
To (i) study the serogroup distribution and virulence characteristics of non-sorbitol-fermenting Escherichia coli isolates from foods of animal origin and cattle faeces and (ii) re-examine the true sorbitol and beta-D-glucuronidase (GUD) reactions of sorbitol-negative (Sor(-)) strains from MacConkey sorbitol agar
Ole Petter Thangstad et al.
Plant molecular biology, 54(4), 597-611 (2004-08-19)
A prototypical characteristic of the Brassicaceae is the presence of the myrosinase-glucosinolate system. Myrosinase, the only known S-glycosidase in plants, degrades glucosinolates, thereby initiating the formation of isothiocyanates, nitriles and other reactive products with biological activities. We have used myrosinase
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