18672
Kaolin
Synonym(s):
Aluminum silicate hydroxide, Bolus, Hydrated aluminum silicate
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About This Item
Linear Formula:
~Al2Si2O5(OH)4
CAS Number:
UNSPSC Code:
12352200
EC Number:
310-194-1
MDL number:
form
powder (finest)
impurities
≤1% Soluble in acid
loss
≤14% loss on ignition, 600 °C
capacity
in accordance absorption capacity
cation traces
Fe: ≤1000 mg/kg, Pb: ≤10 mg/kg
suitability
passes test for identity, passes test for swelling capacity
InChI
1S/2Al.O5Si2.2H2O.2O/c;;1-6(2)5-7(3)4;;;;/h;;;2*1H2;;/q2*+1;-2;;;;
InChI key
NLYAJNPCOHFWQQ-UHFFFAOYSA-N
Application
Kaolin has been used for decreasing the background reading of serum blood sample in enzyme-linked immunosorbent assays (ELISA).
Biochem/physiol Actions
Kaolin also referred to as aluminum silicate hydroxide, bolus or hydrated aluminum silicate is a white clay that reduces the bioavailability of quebracho, tannic acid and quinine. It also activates the plasma factor XII and platelet factor 3 significantly and to few extent platelet-associated factor XI.
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Storage Class
11 - Combustible Solids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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W Van den Broeck et al.
Infection and immunity, 67(2), 520-526 (1999-01-23)
F4 receptor-positive (F4R+) and F4 receptor-negative (F4R-) pigs were orally vaccinated with purified F4 fimbriae of enterotoxigenic Escherichia coli (ETEC). Serum immunoglobulin G (IgG) and IgA responses were readily detected in F4R+ animals, whereas immune responses were not detected in
The effects of collagen and kaolin on the intrinsic coagulant activity of platelets. Evidence for an alternative pathway in intrinsic coagulation not requiring factor XII.
P N Walsh
British journal of haematology, 22(4), 393-405 (1972-04-01)
Nathaniel J Dominy et al.
The Journal of experimental biology, 207(Pt 2), 319-324 (2003-12-12)
Despite occurring in a wide variety of taxa, deliberate soil consumption (geophagy) is a poorly understood behavior. In humans, geophagy is sometimes considered aberrant or a sign of metabolic dysfunction. However, geophagy is normally assigned an adaptive function in nonhuman