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Merck
CN

19364

Sodium butyrate

greener alternative

≥99.0% (GC)

Synonym(s):

Butyric acid sodium salt

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About This Item

Linear Formula:
CH3CH2CH2COONa
CAS Number:
156-54-7
Molecular Weight:
110.09
EC Number:
205-857-6
UNSPSC Code:
12352201
PubChem Substance ID:
329751856
Beilstein/REAXYS Number:
3629439
MDL number:
MFCD00002816

Key Documents

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assay

≥99.0% (GC)

greener alternative product characteristics

Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

impurities

≤4% water

mp

250-253 °C (lit.)

greener alternative category

Enabling

SMILES string

[Na+].CCCC([O-])=O

InChI

1S/C4H8O2.Na/c1-2-3-4(5)6;/h2-3H2,1H3,(H,5,6);/q;+1/p-1

InChI key

MFBOGIVSZKQAPD-UHFFFAOYSA-M

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Other Notes

Agent which alters chromatin structure; Enhanced transfection efficiency and improved cell survival after electroporation of G2/M-synchronized cells and treatment with sodium butyrate.

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GHS07

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Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Sodium butyrate induces new gene expression in Friend erythroleukemic cells.
R Reeves et al.
The Journal of biological chemistry, 254(10), 4283-4290 (1979-05-25)
S Goldstein et al.
Nucleic acids research, 17(10), 3959-3971 (1989-05-25)
To achieve high transfection efficiency in human fibroblasts with good preservation of proliferative capacity we developed an electroporation procedure that combines two distinct modalities: use of recipient cells synchronized in the late G2/mitotic phase of the cell cycle and treatment
Antonello Mai et al.
Journal of medicinal chemistry, 48(9), 3344-3353 (2005-04-29)
Chemical manipulations performed on aroyl-pyrrolyl-hydroxyamides (APHAs) led to (aryloxopropenyl)pyrrolyl hydroxamates 2a-w, and their inhibition against maize HDACs and their class I or class II HDAC selectivity were determined. In particular, from these studies some benzene meta-substituted compounds emerged as highly
Jingbo Xiao et al.
Journal of medicinal chemistry, 54(18), 6215-6233 (2011-08-09)
Spinal muscular atrophy (SMA) is an autosomal recessive disorder affecting the expression or function of survival motor neuron protein (SMN) due to the homozygous deletion or rare point mutations in the survival motor neuron gene 1 (SMN1). The human genome
Jing Jiang et al.
Scientific reports, 5, 9191-9191 (2015-03-18)
Epithelial barrier integrity is critical to maintain the homeostasis in the body. The regulatory mechanism of the epithelial barrier function has not been fully understood. This study aims to elucidate the role of the TWIK-related potassium channel-1 (Trek1) in the
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