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Merck
CN

19667

Butylboronic acid

derivatization grade (GC derivatization), LiChropur, ≥96.0% (T)

Synonym(s):

1-Butaneboronic acid

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About This Item

Linear Formula:
CH3(CH2)3B(OH)2
CAS Number:
Molecular Weight:
101.94
UNSPSC Code:
41116105
NACRES:
NA.22
PubChem Substance ID:
EC Number:
224-607-7
Beilstein/REAXYS Number:
1733489
MDL number:
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InChI key

QPKFVRWIISEVCW-UHFFFAOYSA-N

InChI

1S/C4H11BO2/c1-2-3-4-5(6)7/h6-7H,2-4H2,1H3

SMILES string

CCCCB(O)O

grade

derivatization grade (GC derivatization)

assay

≥96.0% (T)

quality

LiChropur

reaction suitability

reagent type: derivatization reagent
reaction type: Alkylations

technique(s)

gas chromatography (GC): suitable

Quality Level

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Application


  • Developing a reference measurement procedure for free glycerol in human serum by two-step gas chromatography-isotope dilution mass spectrometry.: This research employs butylboronic acid in a reference measurement procedure to quantify free glycerol in human serum. The method is significant for clinical diagnostics, providing accurate and reliable measurements for metabolic studies (Chen et al., 2015).

Other Notes

Derivatizing agent for gas chromatography
Reagent for butylboronate.
Suitable for the derivatization of proximal difunctional compounds (a- and β-hydroxyacids; Ο-phenolic acids; enolizable a-oxo acids; 1,2- and 1,3-diols; enolizable 1,2- and 1,3-ketols; β- and γ-hydroxyamines).

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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D.R. Knapp
Handbook of Analytical Derivatization Reactions (1979)
A. Darbre et al.
Handbook of Derivatives for Chromatography (1970)
[Gas chromatographic separation of the diastereomers of labetalol as n-butylboronate].
T Goromaru et al.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 103(9), 974-978 (1983-09-01)
M Inouye et al.
Japanese journal of medicine, 27(1), 29-33 (1988-02-01)
A highly sensitive and specific quantitative assay for inositol in serum has been developed. Uremic serum, to which hexahydroxybenzene as an internal standard was added, was deproteined with trichloroacetate. The supernatant aqueous phase was taken after lipids in serum were
J O Baker et al.
Biochemical and biophysical research communications, 130(3), 1154-1160 (1985-08-15)
The transition-state-analog inhibitor, 1-butaneboronic acid, markedly enhances the uptake of one g-atom of Zn2+ ions from a metal ion buffer system by Zn-depleted Aeromonas aminopeptidase. In contrast, a substrate-analog inhibitor, n-valeramide, does not perturb the equilibrium between Zn2+ ions and

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