21277
Calpain Inhibitor I
≥97.0% (TLC)
Synonym(s):
ALLN, Ac-LLnL-CHO, MG-101, N-Acetyl-L-leucyl-L-leucyl-L-norleucinal, N-Acetyl-Leu-Leu-Norleu-al
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About This Item
Empirical Formula (Hill Notation):
C20H37N3O4
CAS Number:
Molecular Weight:
383.53
PubChem Substance ID:
UNSPSC Code:
12352200
Beilstein/REAXYS Number:
7656053
MDL number:
biological source
synthetic
assay
≥97.0% (TLC)
form
powder
storage temp.
−20°C
SMILES string
[H]C(=O)[C@H](CCCC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(C)=O
InChI
1S/C20H37N3O4/c1-7-8-9-16(12-24)22-19(26)18(11-14(4)5)23-20(27)17(10-13(2)3)21-15(6)25/h12-14,16-18H,7-11H2,1-6H3,(H,21,25)(H,22,26)(H,23,27)/t16-,17-,18-/m0/s1
InChI key
FMYKJLXRRQTBOR-BZSNNMDCSA-N
Gene Information
human ... CAPN1(823), CTSB(1508), PSMA1(5682)
Other Notes
Shows marked inhibition of cathepsin L
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Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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Justyna M Przystal et al.
Molecular oncology, 7(1), 55-66 (2012-09-07)
Bacteriophage (phage), which are viruses that infect bacteria only, have shown promise as vehicles for targeted cancer gene therapy, albeit with poor efficiency. Recently, we generated an improved version of phage vectors by incorporating cis genetic elements of adeno-associated virus
Sayuri Mizukoshi et al.
Experimental eye research, 91(3), 353-361 (2010-06-16)
The present study was performed to investigate changes of cytosolic and mitochondrial calpain activities, and effects of intravitreously injected calpain inhibitor on photoreceptor apoptosis in Royal College of Surgeon's (RCS) rats. Time courses of activities for both cytosolic and mitochondrial
Yadira Bastián et al.
Reproduction (Cambridge, England), 140(5), 673-684 (2010-08-19)
Research on fertilization in mammalian species has revealed that Ca(2+) is an important player in biochemical and physiological events enabling the sperm to penetrate the oocyte. Ca(2+) is a signal transducer that particularly mediates capacitation and acrosome reaction (AR). Before