21949
6-(4-Carboxyphenyl)-3,8-diamino-5-methylphenanthridinium chloride
≥87.0% (HPLC)
Synonym(s):
4′-Carboxydimidium chloride
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About This Item
Empirical Formula (Hill Notation):
C21H18ClN3O2
CAS Number:
Molecular Weight:
379.84
PubChem Substance ID:
UNSPSC Code:
12352200
Beilstein/REAXYS Number:
4085139
MDL number:
SMILES string
[Cl-].C[n+]1c(-c2ccc(cc2)C(O)=O)c3cc(N)ccc3c4ccc(N)cc14
InChI
1S/C21H17N3O2.ClH/c1-24-19-11-15(23)7-9-17(19)16-8-6-14(22)10-18(16)20(24)12-2-4-13(5-3-12)21(25)26;/h2-11,23H,22H2,1H3,(H,25,26);1H
InChI key
BDPDBMJZOJIFLS-UHFFFAOYSA-N
assay
≥87.0% (HPLC)
storage temp.
−20°C
Other Notes
DNA intercalator. In the synthesis of a DNA capture reagent
Regulatory Information
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J D Harding et al.
Nucleic acids research, 17(17), 6947-6958 (1989-09-12)
We have synthesized and analyzed the functional properties of a novel DNA capture reagent containing a methidium moiety attached to a sepharose bead by a spermine linker. DNA present in a biological fluid or other complex sample binds to the
Kinetics of drug-DNA interaction. Dependence of the binding mechanism on structure of the ligand.
L P Wakelin et al.
Journal of molecular biology, 144(2), 183-214 (1980-12-05)
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