23240
4-Nitrophenyl chloroformate
purum, ≥97.0% (AT)
Synonym(s):
Chloroformic acid 4-nitrophenyl ester
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About This Item
Linear Formula:
ClCO2C6H4NO2
CAS Number:
Molecular Weight:
201.56
EC Number:
231-706-9
UNSPSC Code:
12352101
PubChem Substance ID:
Beilstein/REAXYS Number:
518127
MDL number:
grade
purum
assay
≥97.0% (AT)
bp
159-162 °C/19 mmHg (lit.)
mp
76-82 °C, 77-79 °C (lit.)
storage temp.
2-8°C
SMILES string
[O-][N+](=O)c1ccc(OC(Cl)=O)cc1
InChI
1S/C7H4ClNO4/c8-7(10)13-6-3-1-5(2-4-6)9(11)12/h1-4H
InChI key
NXLNNXIXOYSCMB-UHFFFAOYSA-N
Other Notes
Reagent for the synthesis of mixed, activated carbonates and thiocarbonates, activated urethanes, and other compounds
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signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B - STOT SE 3
target_organs
Respiratory system
Storage Class
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
>230.0 °F
flash_point_c
> 110 °C
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Regulatory Information
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D. Phillips et al.
Tetrahedron Letters, 31, 3291-3291 (1990)
Kai Dong et al.
International journal of nanomedicine, 11, 5109-5123 (2016-10-28)
In this study, a type of multifunctional mixed micelles were prepared by a novel biodegradable amphiphilic polymer (MPEG-SS-2SA) and a multidrug resistance (MDR) reversal agent (d-α-tocopheryl polyethylene glycol succinate, TPGS). The mixed micelles could achieve rapid intracellular drug release and
Zhengjie Yang et al.
Journal of orthopaedic translation, 21, 57-65 (2020-02-27)
The survival rate of osteosarcoma therapy still lags behind overall cancer therapies due to the intrinsic or acquired drug resistance. Developing novel drug delivery systems that may overcome drug resistance would greatly facilitate osteosarcoma therapy. Poly(ethylene glycol) (PEG)-sheddable reduction-sensitive polyurethane