240184
D-Mannitol
≥99%
Synonym(s):
Mannite
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About This Item
Empirical Formula (Hill Notation):
C6H14O6
CAS Number:
Molecular Weight:
182.17
EC Number:
200-711-8
UNSPSC Code:
12352201
MDL number:
Beilstein/REAXYS Number:
1721898
assay
≥99%
optical activity
[α]25/D +141°, c = 0.4 in acidified ammonium molybdate
mp
167-170 °C (lit.)
SMILES string
OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
InChI
1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1
InChI key
FBPFZTCFMRRESA-KVTDHHQDSA-N
Biochem/physiol Actions
A sugar alcohol sweet tastant. Used in sweetness inhibition studies.
Other Notes
This product has been replaced by M4125-Sigma-Aldrich | D-Mannitol ≥98%
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Tian-Rong Li et al.
European journal of medicinal chemistry, 43(8), 1688-1695 (2007-11-27)
Two novel rare earth complexes, Y(III) complex (1) and Eu(III) complex (2), with naringenin-2-hydroxy benzoyl hydrazone ligand were synthesized and characterized. The interaction of the two metal complexes and the free ligand with calf thymus DNA (CT DNA) was investigated
Christopher J Burns et al.
Bioorganic & medicinal chemistry letters, 19(20), 5887-5892 (2009-09-19)
A series of phenylaminopyrimidines has been identified as inhibitors of Janus kinases (JAKs). Development of this initial series led to the potent JAK2/JAK1 inhibitor CYT387 (N-(cyanomethyl)-4-[2-[[4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]-benzamide). Details of synthesis and SAR studies of these compounds are reported.
Markus Bollinger et al.
Journal of medicinal chemistry, 55(2), 871-882 (2011-12-22)
Intervention in integrin-mediated cell adhesion and integrin signaling pathways is an ongoing area of research in medicinal chemistry and drug development. One key element in integrin-ligand interaction is the coordination of the bivalent cation at the metal ion-dependent adhesion site