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Merck
CN

256382

1,2-Dimethoxyethane

spectrophotometric grade, ≥99%

Synonym(s):

mono-Glyme, Dimethylglycol, Ethylene glycol dimethyl ether, Monoglyme

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About This Item

Linear Formula:
CH3OCH2CH2OCH3
CAS Number:
Molecular Weight:
90.12
EC Number:
203-794-9
UNSPSC Code:
12190000
PubChem Substance ID:
Beilstein/REAXYS Number:
1209237
MDL number:
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grade

spectrophotometric grade

vapor density

3.1 (20 °C, vs air)

vapor pressure

48 mmHg ( 20 °C)

assay

≥99%

autoignition temp.

396 °F

expl. lim.

10.4 %

impurities

<0.050% water

evapn. residue

<0.0005%

mp

−58 °C (lit.)

density

0.867 g/mL at 25 °C (lit.)

λ

H2O reference

UV absorption

λ: 220 nm Amax: 1.00, λ: 250 nm Amax: 0.20, λ: 300 nm Amax: 0.03, λ: 350-400 nm Amax: 0.01

SMILES string

COCCOC

InChI

1S/C4H10O2/c1-5-3-4-6-2/h3-4H2,1-2H3

InChI key

XTHFKEDIFFGKHM-UHFFFAOYSA-N

Other Notes

A -D suffix exists for administrative purposes only.
All -D packages are 100% the same product, same quality, same specification as the package sizes previously sold without a -D.



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Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Flam. Liq. 2 - Repr. 1B - Skin Irrit. 2

supp_hazards

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

41.0 °F - closed cup

flash_point_c

5 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

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Peter A Campochiaro et al.
Ophthalmology, 122(3), 545-554 (2014-12-03)
AKB-9778 is a small-molecule competitive inhibitor of vascular endothelial-protein tyrosine phosphatase (VE-PTP) that promotes Tie2 activation and reduces vascular leakage and neovascularization in mouse models. The purpose of this study was to test the safety, tolerability, pharmacokinetics, and biological activity
Andrew Martins et al.
Organic letters, 12(22), 5186-5188 (2010-10-19)
A palladium-catalyzed crossed biaryl coupling/reduction sequence enables the formation of meta-substituted biaryls via solvent-mediated arylpalladium(II) reduction. Isotope labeling studies determined that the decomposition of 1,2-dimethoxyethane (DME) is indeed involved in the reductive process.
Jenn-Huei Lii et al.
Journal of computational chemistry, 24(12), 1490-1503 (2003-07-18)
Ethylene glycol, its dimethyl ether, and some related compounds have been studied using the MM4 molecular mechanics force field. The MM4 calculated structural and energetic results have been brought into satisfactory agreement with a considerable number of experimental data and