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Merck
CN

26155

Sigma-Aldrich

(S)-(−)-2-Chloropropionic acid

puriss., ≥98.5% (sum of enantiomers, GC)

Synonym(s):

(S)-(−)-2-Chloropropanoic acid, L-α-Chloropropionic acid

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About This Item

Empirical Formula (Hill Notation):
C3H5ClO2
CAS Number:
Molecular Weight:
108.52
Beilstein:
1720257
EC Number:
MDL number:
UNSPSC Code:
12352000
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grade

puriss.

Assay

≥98.5% (sum of enantiomers, GC)

optical activity

[α]20/D −14±0.5°, neat

refractive index

n20/D 1.436

bp

185-188 °C

density

1.258 g/mL at 20 °C (lit.)

SMILES string

C[C@H](Cl)C(O)=O

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Other Notes

Chiral building block; it is used in the synthesis of muramic acid derivatives ; Preparation of its tert-butyl ester and reaction with protected amino acid cesium salts to depsipeptides

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H. Paulsen et al.
Liebigs Ann. Chem., 664-664 (1986)
S. Kusumoto et al.
Bulletin of the Chemical Society of Japan, 59, 1411-1411 (1986)
H.G. Lerchen et al.
Tetrahedron Letters, 26, 5257-5257 (1985)

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