27043
Chondroitin 6-sulfate sodium salt from shark cartilage
Synonym(s):
Chondroitin sulfate C sodium salt, Poly[β-glucuronic acid-(1→3)-N-acetyl-β-galactosamine-6-sulfate-(1→4)] alternating
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About This Item
CAS Number:
UNSPSC Code:
12352201
optical activity
[α]20/D −15±5°, c = 1% in H2O
impurities
~3% total nitrogen (N), ~7% total S
loss
≤10% loss on drying
solubility
H2O: 10 mg/mL, clear, colorless
suitability
suitable as substrate for chondroitinase test
Application
Chondroitin, a glucosaminoglycan (GAG), is a polysaccharide chain of alternating units of N-acetylgalactosamine (GalNAc) and glucuronic acid (GlcA) that can be sulfated on the either or both GalNAc and GlcA units. Chondroitin and its sulfates are frequently attached to proteins to form proteoglycans.
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G Cilpa et al.
The journal of physical chemistry. B, 115(16), 4818-4825 (2011-04-05)
A force field has been previously designed for a dodecasaccharide chain of chondroitin-6-sulfate (C6S) and has proved to yield valuable data going from basic conformational properties to a more detailed H-bonding network. This force field is further used here to
Katriina Lipponen et al.
Analytical chemistry, 83(15), 6040-6046 (2011-06-10)
Two different experimental approaches were used for obtaining a comprehensive view and understanding of the interactions between apolipoprotein B-100 (ApoB-100) of low-density lipoprotein and apolipoprotein E (ApoE) of high-density lipoprotein and chondroitin-6-sulfate (C6S) of arterial proteoglycan. The techniques employed were
Antonella Sgambato et al.
Molecules (Basel, Switzerland), 25(19) (2020-09-27)
The regeneration of the nervous system is a challenging task. Currently, regenerative medicine approaches that exploit nature-inspired cues are being studied and hold great promise. The possibility to use protein-based matrices functionalized with small oligo- and monosaccharides is of interest