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Merck
CN

27088

Chromoionophore III

Selectophore

Synonym(s):

9-(Diethylamino)-5-[(2-octyldecyl)imino]benzo[a]phenoxazine, ETH 5350

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About This Item

Empirical Formula (Hill Notation):
C38H55N3O
CAS Number:
Molecular Weight:
569.86
UNSPSC Code:
26111700
NACRES:
NB.61
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
5462368
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product line

Selectophore

Quality Level

form

solid

SMILES string

CCCCCCCCC(CCCCCCCC)C\N=C1/C=C2Oc3cc(ccc3N=C2c4ccccc14)N(CC)CC

InChI

1S/C38H55N3O/c1-5-9-11-13-15-17-21-30(22-18-16-14-12-10-6-2)29-39-35-28-37-38(33-24-20-19-23-32(33)35)40-34-26-25-31(27-36(34)42-37)41(7-3)8-4/h19-20,23-28,30H,5-18,21-22,29H2,1-4H3/b39-35+

InChI key

ICVAQSQRYBGWQH-IGIMMJHKSA-N

General description

Chromoionophore III (ETH 5350) is a pH sensitive dye, and is ratiometric that is the fluorescence spectrum has two peaks, and the ratio between these peaks changes according to the changing pH levels.
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Application

ETH 5350 was used for the fabrication of optode membranes, which are sodium selective, used in order to optically determine sodium in pH-buffered human blood plasma.
Selected application examples
Assay of Na+ activity with solvent polymeric optode membrane prepared from ETH 5350 and sodium ionophore V; Assay of ammonia with solvent polymeric optode membranes based on ETH 5350 and valinomycin (potassium ionophore I)

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Legal Information

Selectophore is a trademark of Merck KGaA, Darmstadt, Germany


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Magnetic microdrill as a modulated fluorescent pH sensor.
McNaughton
Journal of magnetism and magnetic materials, 293 (1), 696-701 (2005)
Characterization of sodium-selective optode membranes based on neutral ionophores and assay of sodium in plasma.
Seiler K
Clinical Chemistry, 37 (8), 1350-1355 (1991)
A A Galyean et al.
The Analyst, 143(2), 458-465 (2017-12-12)
Nanosensors present a biological monitoring method that is biocompatible, reversible, and nano-scale, and they offer many advantages over traditional organic indicators. Typical ionophore-based nanosensors incorporate nile-blue derivative pH indicators but suffer from photobleaching while quantum dot alternatives pose a potential



Global Trade Item Number

SKUGTIN
27088-10MG-F04061833277010