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About This Item
CAS Number:
UNSPSC Code:
12352204
EC Number:
232-671-2
MDL number:
form
powder
specific activity
≥50 U/mg
mol wt
25 kDa, Mr ~25000(lit.)
color
almost white
UniProt accession no.
storage temp.
−20°C
Gene Information
cow ... CTRB1(618826)
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Biochem/physiol Actions
A serine protease that hydrolyzes peptide bonds with aromatic or large hydrophobic side chains (Tyr, Trp, Phe, Met, Leu) on the carboxyl end of the bond.
Other Notes
1 U corresponds to the amount of enzyme, which hydrolyzes 1 μmol Suc-(Ala)2-Pro-Phe-4-NA per minute at pH 7.8 and 25°C
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signalword
Danger
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 1
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Regulatory Information
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J Robyn et al.
Beneficial microbes, 3(4), 299-308 (2012-12-14)
Thermotolerant Campylobacter spp., specifically Campylobacter jejuni and Campylobacter coli, are the most common bacterial causes of human gastroenteritis in developed countries. Consumption of improperly prepared poultry products and cross contamination are among the main causes of human campylobacteriosis. The aim
Llinos G Harris et al.
Applied and environmental microbiology, 79(4), 1393-1395 (2012-12-12)
Staphylococcus aureus and Staphylococcus epidermidis biofilms cause chronic infections due to their ability to form biofilms. The excretions/secretions of Lucilia sericata larvae (maggots) have effective activity for debridement and disruption of bacterial biofilms. In this paper, we demonstrate how chymotrypsin
Saad Khan et al.
PloS one, 7(11), e50547-e50547 (2012-12-12)
In the present study, withaferin A (WA), a steroidal lactone with anti-inflammatory and anti-tumor properties, inhibited proteasome activity and induced endoplasmic reticulum (ER) and cytoplasmic HSP accumulation in Xenopus laevis A6 kidney epithelial cells. Proteasomal inhibition by WA was indicated
Vincent Dechavanne et al.
Protein expression and purification, 87(2), 100-110 (2012-11-14)
The proteasome is a multicatalytic protease complex present in all eukaryotic cells, which plays a critical role in regulating essential cellular processes. During the immune response to pathogens, stimulation by γ interferon induces the production of a special form of
J A Stevens et al.
Insect biochemistry and molecular biology, 43(2), 197-208 (2012-12-19)
The flowers of the ornamental tobacco produce high levels of a series of 6 kDa serine protease inhibitors (NaPIs) that are effective inhibitors of trypsins and chymotrypsins from lepidopteran species. These inhibitors have a negative impact on the growth and
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