27640
O-Phosphorylethanolamine
≥99.0% (T)
Synonym(s):
2-Aminoethyl dihydrogen phosphate, O-Phosphocolamine, O-Phosphoethanolamine, Colaminephosphoric acid
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About This Item
Linear Formula:
NH2CH2CH2OPO3H2
CAS Number:
Molecular Weight:
141.06
EC Number:
213-988-5
UNSPSC Code:
12161700
PubChem Substance ID:
Beilstein/REAXYS Number:
1758916
MDL number:
biological source
synthetic
assay
≥99.0% (T)
form
powder
mp
235-240 °C
solubility
water: 0.1 g/mL, clear, colorless to faintly yellow-green
storage temp.
−20°C
SMILES string
NCCOP(O)(O)=O
InChI
1S/C2H8NO4P/c3-1-2-7-8(4,5)6/h1-3H2,(H2,4,5,6)
InChI key
SUHOOTKUPISOBE-UHFFFAOYSA-N
Other Notes
Potent inhibitor of ornithine decarboxylase
Storage Class
11 - Combustible Solids
wgk
WGK 3
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Regulatory Information
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G M Gilad et al.
Biochemical and biophysical research communications, 122(1), 277-282 (1984-07-18)
Ornithine decarboxylase, which catalyzes the first step in polyamine biosynthesis, is rapidly and transiently increased in various tissues during growth and after various hormonal or noxious stimuli, prior to an elevation in choline kinase activity. Polyamines themselves have been demonstrated
Adilson Kleber Ferreira et al.
PloS one, 8(3), e57937-e57937 (2013-03-22)
Renal cell carcinoma (RCC) is the most common type of kidney cancer, and represents the third most common urological malignancy. Despite the advent of targeted therapies for RCC and the improvement of the lifespan of patients, its cost-effectiveness restricted the
Conan K Wang et al.
The Journal of biological chemistry, 287(52), 43884-43898 (2012-11-07)
Cyclotides are a family of plant-derived circular proteins with potential therapeutic applications arising from their remarkable stability, broad sequence diversity, and range of bioactivities. Their membrane-binding activity is believed to be a critical component of their mechanism of action. Using